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Pain is correlated with other motor and non-motor symptom in Parkinson’s disease

Y. Liu, X.Y. Zhu, X.J. Zhang, S.L. Yang, T.Y. Feng, Y.C. Wu (Shanghai, China)

Meeting: 2018 International Congress

Abstract Number: 1555

Keywords: Constipation, Parkinsonism

Session Information

Date: Monday, October 8, 2018

Session Title: Parkinson's Disease: Non-Motor Symptoms

Session Time: 1:15pm-2:45pm

Location: Hall 3FG

Objective: Study pain occurrence and appearance in Parkinson’s disease (PD), and its relationship with other motor and non-motor symptoms like constipation and footsteps.

Background: The purpose of treatment of Parkinson’s disease is to restore the quality of patients’.

Methods: We reviewed 612 records of outpatients’ department of Parkinson’s disease from 2012 to 2017, and found 296 patients according with UK PD brain bank diagnostic criteria. Brief pain inventory (BPI) was used to described distribution and severity of pain. We classified patients to two groups according to with or without pain. Compared constipation, sleep, mood, fall severity between two groups.

Results: Among 296 patients, there are 186 patients who have pain, the rate is 62.8%. There are 25 patients having headache or neck pain, 18 patients having shoulder or upper limb pain, 5 patients having chest or upper back pain, 108 patients having low back pain, 8 patients having abnormal pain, 38 patients having low limb pain. Among these patients, 142 having have muscle tension pain, 20 having have joint pain, 42 having have neuralgia, 10 having have vascular headache, 8 having have central pain. Pain is related with PDSS, constipation, HAMD, freezing of gait and fall (p<0.01),is not related with gender, age, UPDRS III, MMSE, HAMA or RBD. Low back pain or abdominal pain are related with constipation(p=0.028), PDSS(p=0.013), freezing of gait(p=0.013). Back pain and abdominal pain are related with trending of fall(p=0.058), aren’t related with other factors. If other pain symptoms, excluding low back pain or abdominal pain, they are only related with gender(p<0.01) and sleep quality(p=0.042), aren’t related with fall and constipation.

Conclusions: Pain is a frequent phenomenon in Parkinson’s disease(62.8%). Pain deteriorates the sleep quality, increases freezing of gait, fall rates, especial in low back pain and abdominal pain. Headache and limb pain are more frequent in woman which will influence sleep quality but not constipation and fall.

To cite this abstract in AMA style:

Y. Liu, X.Y. Zhu, X.J. Zhang, S.L. Yang, T.Y. Feng, Y.C. Wu. Pain is correlated with other motor and non-motor symptom in Parkinson’s disease [abstract]. Mov Disord. 2018; 33 (suppl 2). https://www.mdsabstracts.org/abstract/pain-is-correlated-with-other-motor-and-non-motor-symptom-in-parkinsons-disease/. Accessed June 14, 2025.
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