Objective: To describe the prevalence and the impact on the quality of life in patients living with Parkinson’s disease with urinary symptoms.
Background: Parkinson’s disease (PD) is a neurodegenerative motor disorder secondary to basal ganglia dysfunction and also has a variety of intrinsic nonmotor signs like urinary tract symptoms. 1 There are a variety of urinary symptoms in people living with PD some of them are frequency, nocturia, urinary incontinence, and urinary urgency2. However, these symptoms become more troublesome as PD progresses becoming affecting the life quality3 and mental health of the patient leading to a high cause of consults for neurologists treating people with Parkinson’s Disease.
Method: An observational, transversal, retro elective that included patients from a Mexican Institute. A demographic and epidemiologic questionary where applied which determines gender, age, and average evolution of PD for the descriptive statistics. The populations were divided into two groups, having urinary symptoms as a grouping variable. To evaluate urinary symptoms (US) MDS Non-Motor rating scale subdomain H was used. Group 1 patients without US and Group 2 with US. Both groups applied The Parkinson’s Disease Questionnaire (PDQ-39), Hamilton Depression Rating Scale (HRSD), and Hamilton Anxiety Rating Scale (HRSA).
Results: 227 patients were included which 122 were men (53.7%) and 105 were women (46.3%). The average age was 63.3±12.03, with an average diagnosis of PD of 7.29±5.34. The prevalence of urinary symptoms in both groups (N=227) was 70.92%. The punctuation using U Mann-Whitney in PDQ39 was higher in the patients with urinary symptoms (n = 161) than without the urinary symptoms (n = 66) (29±20.42 vs 37.02±22.47, p=0.013), HRSD ( 6.82±5.28 vs 9.4±6.13, p=0.002) and HRSA (6.67±5.35 vs 9.77±6.31, p=<0.001).
Conclusion: The results suggest that urinary symptoms are highly prevalent in the Mexican population and tend to worsen the quality of life and increase the severity of other neuropsychiatric symptoms like anxiety and depression.
References: 1. Claire McDonald, Kristian Winge, David J. Burn, Lower urinary tract symptoms in Parkinson’s disease: Prevalence, etiology and management, Parkinsonism & Related Disorders, Volume 35, 2017, Pages 8-16, ISSN 1353 8020, https://doi.org/10.1016/j.parkreldis.2016.10.0 4.
2.- Campos-Sousa RN, Quagliato E, da Silva BB, de Carvalho RM Jr, Ribeiro SC, de Carvalho DF. Urinary symptoms in Parkinson’s disease: prevalence and associated factors. Arq Neuropsiquiatr. 2003 Jun;61(2B):359-63. doi: 10.1590/s0004-282×2003000300007.
3. Lower urinary tract symptoms in Parkinson’s disease: Prevalence, etiology, and management Citation DataParkinsonism & Related Disorders, ISSN: 1353-8020, Vol: 35, Page: 8-16
To cite this abstract in AMA style:
A. Herrera Ruiz, D. Aguila-Godinez, M. Ruiz-Mafud, M. Medrano-Delgado, A. Domínguez-García, E. Santiago-Delacruz, A. Regalado-Mustafá, M. Medina-Pérez, L. Lira-Juarez,, G. Hernández-Armesto, K. Talavera-Lagunas, J. García-Hernández, A. Hernández-Medrano, D. Romero-Teran, A. Alcocer-Salas, G. Cerda Hernández, A. Abundes-Corona, A. Cervantes-Arriaga, M. Rodríguez-Violante. Prevalence of urinary symptoms and its impact on life quality in patients living with parkinson disease in a mexican population [abstract]. Mov Disord. 2023; 38 (suppl 1). https://www.mdsabstracts.org/abstract/prevalence-of-urinary-symptoms-and-its-impact-on-life-quality-in-patients-living-with-parkinson-disease-in-a-mexican-population/. Accessed June 14, 2025.« Back to 2023 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/prevalence-of-urinary-symptoms-and-its-impact-on-life-quality-in-patients-living-with-parkinson-disease-in-a-mexican-population/