Implementation and Evaluation of a Pre-Clinic Questionnaire to Improve Data Capture and Consultation Efficiency in Parkinson’s Disease Clinics: A Multi-Centre Pilot Study
Objective: To evaluate the feasibility, usability, and clinical value of a pre-clinic questionnaire for patients attending Parkinson’s disease nurse specialist clinics. Background: Parkinson’s disease (PD)…Wearable-Derived Gait Biomarkers Predict Disease Severity and Quality of Life in Parkinson’s Disease: A Machine Learning and Mediation Analysis
Objective: To investigate whether wearable-derived gait biomarkers predict disease severity and health-related quality of life in Parkinson’s disease (PD) and to examine the mediating role…International, multicenter validation study of the Shame in Parkinson’s disease (SPARK) Scale
Objective: To evaluate the psychometric properties of the Shame in PARKinson’s disease (SPARK) Scale in Parkinson’s disease patients, using both classical test theory (CTT) and…Beyond Motor Fluctuations: Non-Motor and Quality-Of-Life Outcomes with Subcutaneous Foslevodopa/Foscarbidopa Infusion in Real-World Practice
Objective: To evaluate motor and non-motor outcomes, including sleep disturbances, of continuous subcutaneous foslevodopa/foscarbidopa infusion in a heterogeneous real-world cohort of patients with advanced Parkinson’s…Impact of Caffeine Consumption on Clinical Phenotype and Non-Motor Symptoms in Parkinson’s Disease
Objective: To determine the impact of daily caffeine consumption (presence, quantity) on the clinical phenotype of patients with Parkinson’s Disease (PD), focusing on age of…A Randomized Controlled Trial Evaluating Ankle Pump Combined with Compression Abdominal Belts on Orthostatic Hypotension in Patients with Parkinson’s Disease
Objective: To investigate the short-term efficacy of ankle pump exercise combined with automated compression abdominal belts on orthostatic hypotension (OH) and orthostatic intolerance symptoms in…The Non-Motor and Extra-Cerebellar Motor Spectrum of Adult-Onset Genetic and Sporadic Cerebellar Ataxias
Objective: To characterize non-motor symptoms (NMS) in patients with Adult-Onset cerebellar ataxia (AOCA) to improve phenotypic characterization and inform targeted therapeutic approaches. Background: AOCA comprises…Exploring “sense of muscle contraction” during gluteus maximus training in Parkinson’s disease: a preliminary EMG perception study
Objective: To explore associations between subjective GMax contraction and surface EMG (sEMG) of GMax, hamstrings (HS), and lumbar extensors (LE) during a standardized hip-extension task.…Sialorrhoea As An Indicator Of Palliative Phase In Advanced Parkinson’s
Objective: 1. To assess whether sialorrhoea severity at referral correlates with advanced Parkinson's 2. Evaluate survival outcomes following clinic attendance3. Explore the potential role of sialorrhoea…Bayesian Network Analysis of Directional Relationships Among Motor and Non-Motor Symptoms in Parkinson’s Disease
Objective: To identify directional relationships among motor and non-motor symptoms in people with Parkinson’s disease (PD) using Bayesian Network analysis and to identify central variables…
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