Session Information
Date: Monday, June 5, 2017
Session Title: Parkinsonism, MSA, PSP (Secondary and Parkinsonism-Plus)
Session Time: 1:45pm-3:15pm
Location: Exhibit Hall C
Objective: The aim of the this study to evaluate different modes of (initial) clinic type of patients with PSP.
Background: Progressive supranuclear palsy (PSP) is a sporadic, adult-onset tauopathy with one of an Parkinson-plus syndromes. PSP has different symptoms such as early postural instability with falls, supranuclear vertical gaze palsy, symmetric akinesia and rigidity. Also, it may has eight varied clinic picture in course.
Methods: Fifteen patient’s with PSP included the study. All patients evaluated according to clinical criteria for the diagnosis of PSP (NINDS-SPSP). Then, reviewed and categorized for different types by the clinician who experienced on the movement disorders.
Results: Nine of the patients were female. The mean age of patients were 65.4. Only two patients were diagnosed PSP with initial symptoms. The other were diagnosed idiopatic Parkinson’s disease by the neurologist. The patients were reviewed by the clinician. Seven patients were included PSP with Richardson’s syndrome (PSP-RS) form. Three patients were included PSP with predominant parkinsonism (PSP-P) form. The other five patients were included mixt form of PSP-RS and PSP-P.
Conclusions: This study with few patients show that PSP is required to an early and accurate diagnosis especially for the different type of clinical spectrum of PSP.
References:
- Litvan I, Agid Y, Calne D, Campbell G, Dubois B, Duvoisin RC, Goetz CG, Golbe LI, Grafman J, Growdon JH, Hallett M, Jankovic J, Quinn NP, Tolosa E, Zee DS. Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop. Neurology. 1996 Jul;47(1):1-9. Review.
- Respondek G, Höglinger GU. The phenotypic spectrum of progressive supranuclear palsy Parkinsonism Relat Disord. 2016 Jan;22 Suppl 1:S34-6. doi: 10.1016/j.parkreldis.2015.09.041. Review.
To cite this abstract in AMA style:
M. Gultekin, R. Baydemir, M.F. Gol, M. Mirza. The phenotypic spectrum of patients with progressive supranuclear palsy [abstract]. Mov Disord. 2017; 32 (suppl 2). https://www.mdsabstracts.org/abstract/the-phenotypic-spectrum-of-patients-with-progressive-supranuclear-palsy/. Accessed June 14, 2025.« Back to 2017 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/the-phenotypic-spectrum-of-patients-with-progressive-supranuclear-palsy/