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The Profile of Cerebellar Ataxia in Neurology Patients at National Tertiary Referral Hospital in Indonesia

I. Permatasari, A. Tiksnadi, D. Tunjungsari (Jakarta, Indonesia)

Meeting: 2024 International Congress

Abstract Number: 1345

Keywords: Ataxia: Clinical features, Early-onset cerebellar ataxia(EOCA), Gait disorders: Clinical features

Category: Ataxia

Objective: This study aimed to portray the profile of Cerebellar Ataxia

Background: Cerebellar ataxia refers to incoordination due to dysfunction of the cerebellum. It can affect balance, gait ataxia, limb movement, oculomotor control, and cognition. These symptoms can significantly impact functional ability and a patient’s quality of life. Early recognition of the initial symptoms and the most common clinical manifestation of cerebellar ataxia is essential for effective management.

Method: Medical record data were collected from neurology outpatient clinic at Dr. Cipto Mangunkusumo Hospital. Data was extracted using the following variables: Demographic data, onset, initial presentation, cerebellar manifestations, other neurological manifestations, classification, and neuroimaging abnormalities.

Results: Twenty-two patients with cerebellar ataxia were included in this study. The most common age group was 18-59 years (77.3%) with median 37 (20-59) years old, and median first hospital visit after onset was 30 (0-240) months. Based on classification, primary cerebellar ataxia had a higher number (86.4%). The most common cerebellar initial presentation was gait ataxia (45.4%), while the most common cerebellar symptoms was dysmetria (22.5%), followed by oculomotor manifestation (16.9%) and gait ataxia (14%). Only 8.5% of the subjects were diagnosed with Pancerebellar Syndrome. Cognitive impairment was the most common associated symptoms (35%). Cerebellar atrophy was seen in 81.8% of the patients, and neuroimaging abnormalities was commonly affected the cerebellar hemisphere (86.5%).

Conclusion: Cerebellar ataxia was dominated by the productive age group, has the most common initial presentation with gait ataxia, and the most common symptom was dysmetria. The brain imaging showed the majority has cerebellar atrophy affecting the cerebellar hemisphere.

To cite this abstract in AMA style:

I. Permatasari, A. Tiksnadi, D. Tunjungsari. The Profile of Cerebellar Ataxia in Neurology Patients at National Tertiary Referral Hospital in Indonesia [abstract]. Mov Disord. 2024; 39 (suppl 1). https://www.mdsabstracts.org/abstract/the-profile-of-cerebellar-ataxia-in-neurology-patients-at-national-tertiary-referral-hospital-in-indonesia/. Accessed June 14, 2025.
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