Objective: To describe a 61-year-old female who presents with abnormal tongue movement found to have right frontoparietal calcifying pseudoneoplasm of the neuraxis (CAPNON).
Background: CAPNON is a rare mass that can occur anywhere in the central nervous system. The cause of CAPNON is unclear and the histopathological findings reveal a calcified fibro-osseous lesion. Tongue fasciculations are an unusual presentation of this lesion.
Method: This is a single case report of a patient whose abnormal presentation and imaging yield the diagnosis of CAPNON. We participated in the multidisciplinary plan of care including chart review regarding this patient’s unique presentation, imaging, and pathological confirmation. There have been no previous case reports of CAPNON with this presentation.
Results: This is a unique case of tongue twitching and numbness lasting for two minutes over the course of two months. The unusual presentation warranted further investigation, including brain MRI revealing a right frontal lesion with edema and calcification. The imaging and pathology revealed findings of CAPNON. The lesion was removed with no complications.
Conclusion: This is the first reported case of CAPNON manifesting these symptoms. The lesion location does not relate to the presentation and more studies are needed to fully understand the pathology of the illness.
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To cite this abstract in AMA style:S. Hudaib, N. Stubbs, L. Simon, V. Blake, E. Nduom, C. Branson. Tongue fasciculations and numbness: A case of calcifying pseudoneoplasm [abstract]. Mov Disord. 2023; 38 (suppl 1). https://www.mdsabstracts.org/abstract/tongue-fasciculations-and-numbness-a-case-of-calcifying-pseudoneoplasm/. Accessed September 23, 2023.
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MDS Abstracts - https://www.mdsabstracts.org/abstract/tongue-fasciculations-and-numbness-a-case-of-calcifying-pseudoneoplasm/