Clinical phenotype (motor and neuropsychological presentation) and neuroimaging in Sardinian patients affected by atypical parkinsonisms, carriers of 20-22 repeats of C9ORF72 hexanucleotide expansion
Objective: Based on our previous finding of the p.A382T of TARDBP in patients with concomitant parkinsonism in the Sardinian population, we hypothesized that also the…Valproate-induced reversible parkinsonism – A case series
Objective: To describe a case series of valproate (VPA)-induced parkinsonism and increase awareness for this condition. Background: VPA as a cause of parkinsonism has been…Relationship between fatigue and sleep disturbances in patients with Parkinson’s disease: A study using Parkinson’s disease sleep scale-2
Objective: To evaluate the relationship between fatigue and sleep disturbances in patients with Parkinson's disease (PD). Background: In patients with PD, fatigue is an important…Rehabilitation of dysphagia in Parkinson’s disease: Effect of chin-down postural maneuver
Objective: To verify the effectiveness of chin-down posture maneuver in the rehabilitation of dysphagia with Parkinson's disease (PD). Background: Although dysphagia is a complicating symptom…The combined effect of REM sleep behavior disorder and hyposmia on cognition and motor phenotype in Parkinson’s disease
Objective: We investigated the relationship between olfactory impairment, REM sleep behavior disorders (RBD), initial cognitive performance and motor phenotype in Parkinson's disease (PD). Background: Olfactory…Detrusor overactivity is associated with frontal dysfunction in patients with Parkinson’s disease?
Objective: To present the prefrontal cortex activity in patients with Parkinson's disease (PD) and evaluated the association between prefrontal cortex and lower urinary tract dysfunction…Alpha-synuclein aggregates of cardiac sympathetic nerves in synucleinopathies and in neurologically unimpaired subjects. Correlation with sympathetic denervation
Objective: To study the cardiac sympathetic innervation and its relationship with the incidence of alpha-synuclein deposits in heart tissue of synucleinopathies and asymptomatic control patients.…Apathy and striatal dopamine defects in non-demented patients with Parkinson’s disease
Objective: We performed this study to investigate whether dopamine depletion in the ventral striatum contributes to apathy in PD. Background: Apathy is a common, disabling…Identification of barriers preventing disclosure of non-motor symptoms in Parkinson’s patients to healthcare providers
Objective: 1) To identify patient barriers to help-seeking for non-motor symptoms (NMS) from their Parkinson's healthcare provider, 2) To determine whether barriers are symptom specific…Identification of premotor Parkinson’s disease
Objective: To evaluate the prevalence of and associations between potential markers of premotor Parkinson's disease (PD) and to estimate the relative risk of these markers…
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