MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    Inferring the coupling of motor related brain areas during paced finger tapping in Parkinson’s patients

    V. Seeger, F. Jung, L. Schneider, T.A. Dembek, P. Reker, N. Apetz, M. Tittgemeyer, L. Timmermann (Cologne, Germany)

    Objective: To analyze the coupling and causal interplay of motor related brain areas in Parkinson's patients during the performance of externally and internally paced finger…
  • 2016 International Congress

    Sensory and motor aspects of rhythmic entrainment in Parkinson’s disease

    E.S. te Woerd, R. Oostenveld, F.P. de Lange, P. Praamstra (Nijmegen, Netherlands)

    Objective: To evaluate entrainment of MEG-recorded brain oscillations induced by a rhythmic task structure in patients with Parkinson's disease (PD). Background: PD patients do not…
  • 2016 International Congress

    Influence of different spike sorting algorithms on the detection of single unit spiking activity in the subthalamic nucleus of patients with Parkinson’s disease

    J. Sukiban, R. Pauli, T.A. Dembek, I. Weber, F. Jung, N. Voges, M. Denker, S. Gruen, L. Timmermann (Cologne, Germany)

    Objective: To determine the most suitable spike sorting algorithm for intraoperatively recorded extracellular currents in the subthalamic nucleus (STN) of patients with Parkinson's disease (PD).…
  • 2016 International Congress

    Dopamine and task-dependent evolution of oscillatory activity in the subthalamic nucleus (STN) and coupling between the STN local field potential and muscle activity in Parkinson’s disease

    U. Ramirez Pasos, R. Reese, F. Steigerwald, M. Reich, C. Matthies, I. Isaias, J. Volkmann (Wuerzburg, Germany)

    Objective: To investigate how subthalamic nucleus local field potentials (STN-LFP) and coupling between STN-LFP and electromyogram (EMG) in static and phasic movements are modulated by…
  • 2016 International Congress

    Heart rate variability to differentiate dementia with Lewy bodies from Alzheimer’s disease in patients with mild cognitive impairment

    J. Yoon, S.M. Lee, J.M. Hong (Suwon, Korea)

    Objective: We aimed to determine whether heart rate variability (HRV) can aid in the differentiation of DLB from AD at the MCI stage. Background: Mild…
  • 2016 International Congress

    Modeling dementia with Lewy bodies using patient-derived neurons

    D.H. Adamowicz, J. Mertens, D.P. Salmon, D.R. Galasko, S. Roy, F.H. Gage (La Jolla, CA, USA)

    Objective: To model Dementia with Lewy bodies (DLB) using neurons derived from patients clinically diagnosed with the disease. Background: A major challenge in neurodegenerative disease…
  • 2016 International Congress

    Catechol-o-methyltransferase Val158Met polymorphism influences prefrontal executive function in early Parkinson’s disease

    Y. Zhang, Y. Zhang, K. Nie, S. Feng, L. Wang, J. Zhao, Z. Huang, L. Wang (Guangzhou, People's Republic of China)

    Objective: The Catechol-O-Methyltransferase (COMT) Val158Met polymorphism has been proposed to be associated with increased risk of PD and have a specific impact on dopamine-mediated prefrontal…
  • 2016 International Congress

    Genetic factors influencing frontostriatal dysfunction and the development of dementia in Parkinson’s disease

    I. Huertas Fernandez, S. Jesus, F.J. Garcia Gomez, J.A. Lojo, I. Bernal Bernal, M. Bonilla Toribio, J.F. Martin Rodriguez, D. Garcia Solis, P. Gomez Garre, P. Mir (Sevilla, Spain)

    Objective: To investigate the role of APOE, MAPT, COMT, SNCA and GBA genes in both striatal dopaminergic denervation and the development of dementia in Parkinson's…
  • 2016 International Congress

    Occurrence and pattern of cognitive deficits in prodromal Parkinson’s disease

    C. Pausch, J. Spiegel, F.A. Wollenweber, C. Bayer, U. Dillmann, K. Fassbender, S. Behnke (Homburg Saar, Germany)

    Objective: To assess a possible cognitive impairment and its specific profile in the prodromal phase of Parkinson's disease (PD). Background: Cognitive impairment is common in…
  • 2016 International Congress

    Monoaminergic biomarkers of cognitive decline in Parkinson’s disease and Lewy body dementia

    S. van der Zee, Y. Vermeiren, T. Aerts, D. van Dam, M.J. Gerritsen, J.M. Spikman, T. van Laar, P.P. de Deyn (Groningen, Netherlands)

    Objective: The objective of this study was the identification of biochemical markers of cognitive impairment in Parkinson's disease (PD) and dementia with Lewy bodies (DLB)…
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