A comparison of standards of care in Parkinson’s disease between a general neurology clinic and a specialist movement disorders clinic based on the UK NICE guidelines
Objective: To compare standards of care for patients with Parkinson's disease (PD) between a general neurology clinic and specialist movement disorders clinic based on the…Parkinsonism due to hypermanganism in the background of cirrhosis and recovery by CaNaEDTA
Objective: To present a patient diagnosed with secondary hypermanganism due to cirrhosis whose extrapyramidal findings had recovered significantly after chelation therapy. Background: Manganese is an…The neurosteroid dehydroepiandrosterone sulfate (DHEAS) reverses the dopaminergic deficiencies in mild hepatic encephalopathy: A possible therapeutic issue for the management of parkinsonism in cirrhotic patients
Objective: In the present study, we describe the changes of the dopaminergic system occurring in the cirrhotic rats and concomitantly we investigated the effect of…The role and underlying mechanisms of BAG3 in regulating autophagy in PC12 cells
Objective: To detect the role of Bcl-2-associated athanogene 3 (BAG3) in regulating autophagy in PC12 cells and explore the underlying mechanisms of it. Background: Increasing…The correlation between dietary fiber, fluid intake and constipation in patients with Parkinson’s disease
Objective: To clarify the correlation between high dietary fiber, fluid intake and constipation in Parkinson's disease (PD) patients. Background: Constipation is one of the complications…Balance training in individual’s with Parkinson’s disease: Therapist-supervised vs. home-based exercise programmes
Objective: To evaluate and compare the efficacy of a home-based balance programme to therapist-supervised programme on gait parameters, dynamic balance, balance confidence and motivation in…The effect of Mozart piano sonata on Parkinsonian tremor, rigidity and bradykinesia
Objective: In this study we intend to assess the effect of Mozart piano sonata on Parkinsonian tremor. Background: The effect of rhythmic auditory stimulation and…Suggested criteria for patient selection for therapy with carbidopa/levodopa enteral suspension (CLES)
Objective: To provide suggested guidance on how to select appropriate candidates for therapy with carbidopa/levodopa enteral suspension (CLES) based on published literature. Background: The introduction…The novel COMT-inhibitor ODM-104 and optimized carbidopa in combination with modified release levodopa reduce levodopa fluctuation and increase minimum concentrations in healthy subjects, when compared to the standard carbidopa/levodopa/entacapone combination
Objective: To evaluate the plasma pharmacokinetics (PK) of orally administered modified release (MR) levodopa in combination with the aromatic L-amino acid decarboxylase inhibitor carbidopa and…Therapy escalation in Parkinson’s disease – The TEMP trial, a regional survey
Objective: To assess socio-demographic and disease specific data in patients with Parkinson's disease (PD) before and one year after therapy escalation with subcutaneous apomorphine (APO),…
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