Nigrostriatal degeneration and serum BDNF levels in patients with “de novo” untreated Parkinson’s disease
Objective: To evaluate serum Brain-Derived NeurotrophicFactor(BDNF) levels in “de novo” untreated Parkinson's disease (PD) patients and their relationship to nigrostriatal degeneration measured with [123I]FP-CIT SPECT.…Multimodal imaging assessment of nigrostriatal pathway in Parkinson’s disease using 11C-PE2I PET and neuromelanin-sensitive MR
Objective: To evaluate the nigrostratal pathway with multimodal assessment using striatal 11C-PE2I PET and nigral Neuromelanin-sensitive MR in Parkinson's disease. Background: The main pathological features…Diffusion tensor imaging of the corticospinal tract differentiates Parkinson’s disease (PD) patients from controls
Objective: To asses white matter tractography of the corticospinal tract in PD patients. Background: Since the diagnosis of PD is still based on clinical assessment,…Frontal cortex grey matter integrity determines motor improvement after STN-DBS in patients with Parkinson’s disease
Objective: We hypothesize that the integrity of the cortical structures is an independent predictor for the DBS response. Background: Deep brain stimulation of subthalamic nucleus…Is it just a coincidence? Three new cases of Parkinson’s disease associated with myasthenia gravis
Objective: To introduce three new cases of Parkinson's disease (PD) patients who developed Myasthenia gravis (MG) and to review clinical features and diagnostic approaches of…Ultra high field magnetic resonance imaging of nigrosome 1 is a biomarker of new onset and premotor Parkinson’s disease
Objective: An unmet need exists to develop a methodology to diagnose Parkinson's disease (PD) in the premotor stage, so that patients can be enrolled in…Lessons-experienced in the creation of a global public-private consortium with the goal of advancing treatments that hold most potential for delayed disease progression in Parkinson’s disease – Critical path for Parkinson’s (CPP)
Objective: The path is summarized that led to the creation of a global public-private-partnership uniting an international non-profit charity, Parkinson's UK, a global non-profit organization,…Gender differences in DLB: frequency, clinical presentation and treatment
Objective: To describe demographic and clinical characteristics and use of cholinesterase inhibitors in women and men diagnosed with DLB. Background: DLB seems to be more…Social cognition assessment in progressive supranuclear palsy: The cognitive interface with frontotemporal dementia
Objective: To explore the cognitive profile of PSP patients in tests of social cognition and to compare their performance to patients with behavioural variant frontotemporal…The relationship between cognitive aspects (education status, executive function and verbal fluency) and motor aspects (balance and gait) in patients with Parkinson’s disease
Objective: The aim of this study was to verify if there would be correlations between cognitive variables (educational status, executive function, verbal fluency) and motor…
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