The correlation between dietary fiber, fluid intake and constipation in patients with Parkinson’s disease
Objective: To clarify the correlation between high dietary fiber, fluid intake and constipation in Parkinson's disease (PD) patients. Background: Constipation is one of the complications…Balance training in individual’s with Parkinson’s disease: Therapist-supervised vs. home-based exercise programmes
Objective: To evaluate and compare the efficacy of a home-based balance programme to therapist-supervised programme on gait parameters, dynamic balance, balance confidence and motivation in…The effect of Mozart piano sonata on Parkinsonian tremor, rigidity and bradykinesia
Objective: In this study we intend to assess the effect of Mozart piano sonata on Parkinsonian tremor. Background: The effect of rhythmic auditory stimulation and…Suggested criteria for patient selection for therapy with carbidopa/levodopa enteral suspension (CLES)
Objective: To provide suggested guidance on how to select appropriate candidates for therapy with carbidopa/levodopa enteral suspension (CLES) based on published literature. Background: The introduction…The novel COMT-inhibitor ODM-104 and optimized carbidopa in combination with modified release levodopa reduce levodopa fluctuation and increase minimum concentrations in healthy subjects, when compared to the standard carbidopa/levodopa/entacapone combination
Objective: To evaluate the plasma pharmacokinetics (PK) of orally administered modified release (MR) levodopa in combination with the aromatic L-amino acid decarboxylase inhibitor carbidopa and…Therapy escalation in Parkinson’s disease – The TEMP trial, a regional survey
Objective: To assess socio-demographic and disease specific data in patients with Parkinson's disease (PD) before and one year after therapy escalation with subcutaneous apomorphine (APO),…Safety and efficacy of pardoprunox for patients with Parkinson’s disease: A meta-analysis
Objective: The aim of this meta-analysis is to synthesize evidence from published randomized controlled trials (RCTs) about the safety and efficacy of Pardoprunox for Patients…Levodopa-carbidopa intestinal gel in routine care of advanced Parkinson’s disease patients: Final long-term efficacy results on motor complications from the GLORIA registry
Objective: To evaluate the effect of levodopa-carbidopa intestinal gel (LCIG, designated in the United States as carbidopa-levodopa enteral suspension) on motor fluctuations and dyskinesia in…The influence of cerebellar transcranial direct current stimulation on skill acquisition in Parkinson’s disease
Objective: The purpose was to determine the influence of cerebellar transcranial direct current stimulation (c-tDCS) on motor skill acquisition in Parkinson's disease (PD). Background: c-tDCS…DIRECT DBS: A prospective, multi-center clinical trial with blinding for a directional DBS lead
Objective: DIRECT DBS is an exploratory study which will investigate the effects of subthalamic deep brain stimulation (DBS) using directional DBS leads with current steering…
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