Disease severity is not predictive of the dose required for apomorphine sublingual film (APL-130277) to convert a patient with Parkinson’s disease from OFF to fully ON
Objective: Evaluate whether baseline disease severity is predictive of the effective APL-130277 dose to turn a patient with Parkinson's disease (PD) from OFF to fully…Increased cerebrospinal fluid lactate levels in Parkison’s disease: Is it a proof of mitochondrial inefficiency?
Objective: The aim of the present study was to investigate the impairment of neuronal energy metabolism, as measured by means of cerebrospinal fluid (CSF) lactate…Cognitive and depressive behavior changes in aged mice with heterozygous deletions of VMAT2 or of DAT
Objective: To evaluate cognitive and depressive behavior in aged mice with heterozygous deletions of vesicular monoamine transporter (VMAT2) or of Dopamine transporter (DAT). Background: VMAT2…Intrastriatal injection of ionomycin profoundly changes motor response to L-DOPA and its underlying molecular mechanisms
Objective: We investigated whether intrastriatal injection of ionomycin to hemiParkinsonian rats produced changes in L-DOPA responses including LID and analyzed the effects of ionomycin on…Drug-induced parkinsonism in Taiwan
Objective: To review drug-induced parkinsonism (DIP) in Taiwan. Background: Drug-induced parkinsonism (DIP) is a frequent etiology of secondary parkinsonism. DIP must always be suspected when…Hemifacial spasm – Therapeutic assessment of botulinum toxin
Objective: To evaluate the long-term effect of botulinum toxin type A (BTX-A) in the treatment of hemifacial spasm (HFS) in a large group of patients…NREM parasomnias as a marker of cognitive impairment in Parkinson’s disease
Objective: To identify potential sleep markers of cognitive impairment in Parkinson's disease (PD) exploring the relationship between V-PSG findings and clinical features. Background: Sleep disorders…Hemi-stereotypies symptomatic to aneurysm: Differential diagnosis of tardive dyskinesia
Objective: Below we present the case of a hemi-stereotypies symptomatic to aneurysm of the middle cerebral artery presented in mass effect on the subthalamic nucleus…An optimized formulation of velocity distribution in digital spiral analysis to differentiate essential tremor and Parkinson’s disease
Objective: Using optimization formula of different visuo-motor parameter in digital spirogram to differentiate patients with essential tremor from Parkinson's disease. Background: Early-stage Parkinson's disease (PD)…Structural and functional signature of primary orthostatic tremor
Objective: (1) We aimed to characterize, in primary orthostatic tremor (OT), the structural and functional defects in the cerebellar motor pathways; (2) We correlated the…
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