Efficacy of 4845 botulinum toxin (BoNT) treatment cycles, and clinical strategies after a failed cycle
Objective: To explore 1) relationship between peak benefit and Duration of Adequate Response (DAR) after BoNT, 2) frequency & causes of secondary Treatment Failure (TF),…Copper chelation efficacy of alginate/chitosan based D-penicillamine nanoparticles in rat model of non-Wilsonian brain copper toxicosis
Objective: To evaluate the copper (Cu) chelation efficacy of orally administered D-penicillamine loaded nanoparticles to that of conventional D-penicillamine therapy for 90 days in Wistar…A double-blind randomized controlled trial of cognitive training for freezing of gait in Parkinson’s disease
Objective: To investigate the potential of cognitive training to improve symptoms of freezing of gait in Parkinson's disease. Background: Freezing of gait (FOG) is a…Lead angle matters: Side effects of deep brain stimulation improved with adjustment of lead angle
Objective: A variety of technical considerations influence the outcome of Deep Brain Stimulation (DBS). We highlight a case where revising the angle of approach significantly…Non-motor outcomes of subthalamic stimulation in Parkinson’s disease depend on the location of active contacts
Objective: To investigate the impact of active electrode contact location on non-motor outcomes in patients with Parkinson's disease (PD) and subthalamic nucleus (STN) deep brain…Is inter-limb coupling modified by subthalamic deep brain stimulation and dopaminergic medication in Parkinson’s disease?
Objective: We characterized different aspects of bimanual coordination in patients with PD, including inter-limb coupling, and then determined whether they were altered by therapeutic modulation…Stimulation of the globus pallidus internus in the treatment of Parkinson’s disease: Long-term results of a monocentric follow-up
Objective: To investigate the long-term outcome of pallidal deep brain stimulation (GPi-DBS) in Parkinson's disease (PD). Background: GPi-DBS is beneficial in patients with advanced levodopa-responsive…The effects of 60 Hz frequency of STN-DBS on gait in Parkinson’s disease
Objective: To evaluate the effect of low frequency (60Hz) deep brain stimulation of the subthalamic nucleus (STN-DBS) on gait in patients with Parkinson's disease (PD)…The effect of short pulse width neurostimulation in GPi-DBS
Objective: To evaluate (1) clinical usefulness and (2) adverse effects of thirty microseconds pulse width stimulation in deep brain stimulation of the globus pallidus internus…Incidence and characteristics of gait dysfunction after subthalamic nucleus deep brain stimulation
Objective: To identify the effects of subthalamic nucleus deep brain stimulation on gait kinematics in patients with PD and describe the incidence of gait dysfunction…
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