Inhibition of nociceptive responses by modulating serotonergic signals at the rostral ventromedial medulla in 6-OHDA-induced Parkinson’s disease rat model
Objective: We aimed to determine whether the descending 5-HT facilitatory pathway from rostral ventromedial medulla (RVM) and the extracellular 5-HT in RVM are involved in…α-synuclein in peripheral organs decreases in Lewy body disease complicated by Alzheimer’s disease
Objective: To examine whether the degree of α-synuclein (α-Syn) in the peripheral organs of patients with Lewy body disease (LBD: Parkinson's disease, dementia with Lewy…Evaluating the natural history of prodromal PD in the PARS cohort
Objective: An objective of the Parkinson Associated Risk Syndrome (PARS) study is to identify a cohort 'at risk' for Parkinson's disease (PD) using sequential olfactory…Midbrain atrophy differentially progresses between Richardson’s Syndrome, progressive supranuclear palsy-parkinsonism and Parkinson’s disease: Longitudinal MRI study
Objective: To elucidate different patterns of progression in midbrain atrophy between patients with Richardson's syndrome (PSP-RS), progressive supranuclear palsy-parkinsonism (PSP-P), and Parkinson's disease (PD) using…Application and correlates of the PSP quality of life scale
Objective: To apply the PSP Quality of Life scale (PSP-QoL) within a cross-sectional PSP population and correlate these scores with those of the PSP rating…Three cases of neuronal intranuclear inclusion disease (NIID)
Objective: Here, we present three NIID cases. One of them, autopsy was performed. Background: Neuronal intranuclear inclusion disease (NIID)(OMIM 603472) is a neurodegenerative disorder characterized…A polysomnography study of REM sleep without atonia and REM sleep behavior disorder in MSA and PD
Objective: The aim of this study was to perform a cross-sectional comparative analysis of quantitative REM sleep without atonia (RWA) and REM sleep behavior disorder…PROSPECT: A UK-based longitudinal observational study of PSP, CBD, MSA and atypical parkinsonism syndromes
Objective: To aid the development of curative treatments, we need to develop better methods for diagnosing Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD) and Multiple…The effects of fluvoxamine maleate in a post-natal stress rat model of neurodegeneration
Objective: In this study, we investigated whether treatment of anxiety-like symptoms with Fluvoxamine maleate alleviates the neurotoxic effects of 6-OHDA in a Parkinsonian rat model.…Systematic literature review of droxidopa in clinical trials for neurogenic orthostatic hypotension (nOH) in parkinsonism
Objective: The aim of this study was to review the published evidence for the efficacy, safety, and dosing practices of droxidopa treatment for symptomatic neurogenic…
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