Subjective report does not predict objective swallow impairment in atypical Parkinsonian syndromes
Objective: Swallow and speech disturbances are common in patients with atypical parkinsonism. The emergence of swallowing problems, or dysphagia, is associated with increased morbidity and…Cognitive impairment in patients with progressive supranuclear palsy and multiple system atrophy
Objective: Assessment, description and mutual comparison of cognitive impairment in patients with progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). Background: In most recent…Clinical phenotype (motor and neuropsychological presentation) and neuroimaging in Sardinian patients affected by atypical parkinsonisms, carriers of 20-22 repeats of C9ORF72 hexanucleotide expansion
Objective: Based on our previous finding of the p.A382T of TARDBP in patients with concomitant parkinsonism in the Sardinian population, we hypothesized that also the…Valproate-induced reversible parkinsonism – A case series
Objective: To describe a case series of valproate (VPA)-induced parkinsonism and increase awareness for this condition. Background: VPA as a cause of parkinsonism has been…Relationship between fatigue and sleep disturbances in patients with Parkinson’s disease: A study using Parkinson’s disease sleep scale-2
Objective: To evaluate the relationship between fatigue and sleep disturbances in patients with Parkinson's disease (PD). Background: In patients with PD, fatigue is an important…Rehabilitation of dysphagia in Parkinson’s disease: Effect of chin-down postural maneuver
Objective: To verify the effectiveness of chin-down posture maneuver in the rehabilitation of dysphagia with Parkinson's disease (PD). Background: Although dysphagia is a complicating symptom…The combined effect of REM sleep behavior disorder and hyposmia on cognition and motor phenotype in Parkinson’s disease
Objective: We investigated the relationship between olfactory impairment, REM sleep behavior disorders (RBD), initial cognitive performance and motor phenotype in Parkinson's disease (PD). Background: Olfactory…Detrusor overactivity is associated with frontal dysfunction in patients with Parkinson’s disease?
Objective: To present the prefrontal cortex activity in patients with Parkinson's disease (PD) and evaluated the association between prefrontal cortex and lower urinary tract dysfunction…Alpha-synuclein aggregates of cardiac sympathetic nerves in synucleinopathies and in neurologically unimpaired subjects. Correlation with sympathetic denervation
Objective: To study the cardiac sympathetic innervation and its relationship with the incidence of alpha-synuclein deposits in heart tissue of synucleinopathies and asymptomatic control patients.…Apathy and striatal dopamine defects in non-demented patients with Parkinson’s disease
Objective: We performed this study to investigate whether dopamine depletion in the ventral striatum contributes to apathy in PD. Background: Apathy is a common, disabling…
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