Autosomal Dominant Spinocerebellar Ataxia Secondary to CACNA1G in a Patient of German Ancestry
Objective: We describe the case of a male patient of German ancestry with SCA 42. Background: Hereditary spinocerebellar ataxia (SCA) describes a heterogeneous group of…New XK deletion associated with McLeod syndrome
Objective: To describe a new XK deletion associated with McLeod syndrome. Background: McLeod syndrome is a rare genetic syndrome characterized by the association of chorea…White matter lesions and peripheral vessel reactivity in dementia with Lewy bodies
Objective: We aimed to assess the significance of white matter hyperintensities (WMHs) in dementia with Lewy bodies (DLB) and their contribution to phenotype of the…Cefepime-induced encephalopathy and myoclonus
Objective: To raise awareness of cephalosporin-induced encephalopathy and myoclonus. Background: Myoclonus occurs in 15% of antibiotic-associated encephalopathy, especially with penicillins and cephalosporins. Cefepime and ceftazidime…MRI-based Brain Networks of Perfusion and Structural Abnormalities in Patients with Cerebellar Variant of Multiple System Atrophy
Objective: To identify MRI-based brain networks of cerebral perfusion and structural abnormalities in cerebellar variant of MSA. Background: MSA consists clinically of parkinsonian (MSA-P) and cerebellar (MSA-C) variants. Previous FDG PET studies have…Striatal dopamine transporter abnormalities in pure autonomic failure and speculation about the relationship with Lewy bodies
Objective: To reveal dopamine transporter (DAT) abnormalities in pure autonomic failure (PAF) and speculate about the relationship with the Lewy body progression pathway. Background:…Piper betle L. Attenuates 6-OHDA Induced Apoptosis in SH-SY5Y Cells and Neuronal Injury in Caenorhabditis elegans Parkinson’s Model
Objective: To explore the anti-apoptotic effects of Piper bitle leaf extract (PLE) on 6-OHDA induced cellular injury in human neuroblastoma cell SH-SY5Y. To analyse the neuroprotective…Effects of TRH therapy on the prism adaptation task in patients with spinocerebellar degeneration.
Objective: To reveal effects of TRH therapy on the prism adaptation task in patients with spinocerebellar degeneration (SCD). Background: TRH [Thyrotropin releasing hormone (protirelin tartrate)]…The Impact of Cognitive Changes on Everyday Life for People with Parkinson’s: The Patient’s Perspective
Objective: To understand the patient’s perspective about cognitive changes in Parkinson’s disease and about the impact of cognitive dysfunction on daily life. Background: Cognitive dysfunction is…Quantifying reinforcement learning deficits in early stage Parkinson’s patients using a strategic decision-making task
Objective: 1.Characterize deficits in reinforcement learning processes in PD during a strategic game analogous to Rock-Paper-Scissors (RPS). 2.Examine the effects of dopaminergic (DA) treatment on…
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