Action Verbal Fluency is Related to the Functional Integrity of the Cognitive Cortico-Striatal Loop in Parkinson’s Disease
Objective: The objective of this study is to investigate the relationship between action verbal fluency (the capacity to name as many action words as possible…Oscillatory dynamics of impaired novelty detection at early Parkinson’s disease
Objective: In this work we aimed to describe the brain oscillations associated with impaired novelty detection at early PD. Background: Cognitive impairment, especially attentional and…Understanding the role of LRRK2 in Indian population
Objective: Genomic approaches in Caucasian population show little transferability to other ethnically diverse populations such as Indian population. Understanding the genetic architecture of a disease…Mitochondrial DNA variants function as potential genetic risk factors for Parkinson disease
Objective: To understand whether mtDNA variants contribute to the susceptibility to sporadic PD. Background: It is well-recognized that mitochondrial (mt) dysfunction is involved in the…Genetic, epigenetic and expression profiles in alpha-synucleinopathies
Objective: To determine whether each of the alpha-synucleinopathies has distinct methylation and/or expression profiles that distinguishes them from other disorders in this class. Background: The…Gene associated differences in pre-diagnostic symptoms of Parkinson’s Disease: a retrospective study
Objective: To investigate whether glucocerebrosidase (GBA) L444P and leucine-rich repeat kinase 2 (LRRK2) G2385R and R1628P mutations are associated with different symptoms and manifesting patterns…Treatment of Parkinson’s disease psychosis–a systematic review of RCTs
Objective: An SLR was conducted to assess the evidence from RCTs supporting the safety and efficacy of Parkinson’s disease psychosis (PDP) treatments. Background: PDP is…Gait characteristics of freezing in patients with Parkinson’s disease
Objective: To investigate gait characteristics of FOG, this study analyzed forward and backward gait of PD patients. Background: FOG is one of major risk factors…Development and validation of diagnostic criteria for advanced Parkinson disease: the CDEPA questionnaire
Objective: Using the Delphi methodology we previously obtained a consensus on the definition and clinical characteristics of advanced Parkinson’s disease (APD). We aimed to develop…Parkinson’s disease subtypes correlate with clinical severity: a Brazilian population study
Objective: To correlate Parkinson's disease (PD) subtypes with a clinical severity in a Brazilian population sample. Background: Current studies have shown that PD may comprise…
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