Alteration of early endosomal trafficking causes neurodegeneration in PARK20
Objective: To elucidate the molecular basis of the Park20 by evaluating the role of synaptojanin 1 in intracellular trafficking. Background: Recently a new form of…Full sequencing and GWAS markers analysis of SNCA in RBD and progression to synucleinopathies.
Objective: To study the role of SNCA variants in REM sleep Behavior Disorder (RBD) and progression to synucleinopathies. Background: Individuals with properly diagnosed idiopathic RBD…Early-Onset Parkinsonism and Short Stature in a Puerto Rican Kindred. Possible DJ1 deletion?
Objective: We aim to identify and describe the clinical phenotype associated with a Puerto Rican family with early-onset PD and short stature. Background: As few…Improving Diagnosis and Treatment of Anxiety in Parkinson’s Disease: IDATA-PD Study
Objective: We investigated PD-specific features of anxiety for clear conceptualisation, and assessed targeted psychotherapy for anxiety in Parkinson’s disease (PD). Background: Anxiety is poorly diagnosed in PD…Neurological examination of motor Functional Neurological Disorders: an evidence-based review towards the development of consensus guidelines from the Committee on Research of the ANPA
Objective: To develop evidence-based consensus recommendations for the neurological examination of motor Functional Neurological Disorders (FND)/Conversion Disorder, weakness and abnormal movements, on behalf of the…Factors associated with occurrence of motor complications among Parkinson’s disease patients with levodopa treatment in Estonia
Objective: To identify the factors associated with the occurrence of motor complications among patients with Parkinson’s disease (PD) who receive levodopa treatment. Background: Levodopa is the…The French version of the Munich Dysphagia Test-Parkinson’s disease (MDT-PD): Translation and validation in a multilingual population of the Luxembourg Parkinson’s Study (HELP-PD).
Objective: To provide and validate a French translation of the MDT-PD in the Luxembourgish multilingual population, in terms of linguistic, test-retest-, language reliability and sensitivity.…Tic Severity and Treatment in Children: The Effect of Comorbid Attention Deficit Hyperactivity Disorder and Obsessive Compulsive Behaviours
Objective: This study sought to understand how the presence, severity and treatment of Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD) influence tic…Rationale and Design of a Phase 2 Study to Evaluate the Efficacy of Intepirdine (RVT-101) in Improving Gait and Balance in Patients with Dementia
Objective: To describe the rationale and design of a Phase 2 study that evaluates the effect of intepirdine (RVT-101) on gait and balance in patients…Parkinsonics – A Prospective, Randomized, Blinded, Cross-Over Trial of Group Singing for Motor and Non-Motor Symptoms in Idiopathic Parkinson Disease (PD)
Objective: To assess the effects of weekly group singing on PD patients’ objective vocal and motoric function, cognition, mood, self-efficacy and quality of life. Background:…
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