Virtual research visits in individuals with Parkinson disease enrolled in a clinical trial: REACT-PD Study Interim Analysis
Objective: To demonstrate the feasibility, reliability, and value of conducting web-based clinical trial assessments in individuals with Parkinson disease (PD). Background: Increasing interest has been…Focused ultrasound subthalamotomy for Parkinson’s disease: A pilot study
Objective: To evaluate feasibility, safety and effectiveness of unilateral subthalamotomy performed with MRIgHIFU to treat the cardinal motor features of PD Background: Ablative functional neurosurgery for…Movement disorder specialists’ determination of eligibility for device aided treatment in advanced Parkinson’s disease: Results from the OBSERVE-PD study
Objective: To characterize the clinical and non-clinical features of ‘advanced’ PD patients considered to be eligible or ineligible for device-aided treatment (DAT) options by movement…The occurrence of dopamine-responsive and dopamine-resistant resting tremor in Parkinson’s disease
Objective: To investigate dopamine-responsiveness of resting tremor in Parkinson’s disease Background: Unlike the core Parkinson motor symptom, bradykinesia, resting tremor has a variable response to…A novel paradigm of variable frequency deep brain stimulation to improve freezing of gait in Parkinson’s disease
Objective: To determine the effects of a novel deep brain stimulation (DBS) paradigm of combining high and low frequency stimulation in varying patterns (VFS) for…Evolution in Dopamine Transporter (DaT) Scan Utilization Patterns and its Effect on Treatment Decisions: Results of the Next 200 Scans
Objective: To describe further changes in DaT scan utilization and its influence on management following our initial experience. Background: We previously reported our DaT scan…Metabolic changes following transcranial magnetic resonance-guided focused ultrasound subthalamotomy
Objective: As part of a pioneer trial to investigate the use of transcranial magnetic resonance-guided focused ultrasound subthalamotomy (MRgFUS-STN) in Parkinson's disease (PD), this study addresses…Speech difficulties are linked to striatal dopaminergic deficits and cognitive decline in early de novo patients with Parkinson’s disease
Objective: To investigate whether speech difficulties are associated with striatal dopaminergic deficits and whether are linked to progression of symptoms in early de novo patients…Decreased Fronto-Parietal connection is associated with face pareidolia in Parkinson’s disease.
Objective: To investigate the neural mechanism of face pareidolia in Parkinson’s disease (PD) patients using resting state functional magnetic resonance imaging (rs-fMRI). Background: Face pareidolia…Dopamine depletion impairs gait automaticity by altering cortico-striatal and cerebellar processing in Parkinson’s disease
Objective: Investigating the role of dopaminergic medication on the neural mechanisms underlying lower limb motor automaticity during fMRI in 23 patients with PD that were…
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