The spectrum of composite autonomic severity score in SCA1, SCA2 and SCA3 patients
Objective: To analyze composite autonomic severity score in patients of spinocerebellar ataxia types 1, 2 and 3. Background: Spinocerebellar ataxia (SCA) is a progressive neurodegenerative…Steroid-responsive encephalopathy with associated thyroiditis (SREAT) presenting with pure cerebellar ataxia
Objective: To describe two patients with SREAT presenting with progressive cerebellar ataxia. Background: SREAT or Hashimoto’s encephalopathy is an autoimmune encephalopathy typically presenting with rapidly…Metabolic pattern of acute hemichorea associated with contralateral carotid stenosis
Objective: To investigate the metabolic pattern of acute hemichorea associated with contralateral carotid artery stenosis and no lesion on structural brain imaging, using brain 18F-FDG-PET.…Neurofilament light chain levels in cerebrospinal fluid do not discriminate between patients with prion disease and mimics
Objective: To determine whether levels of neurofilament light chain (NFL) in cerebrospinal fluid (CSF) are useful to discriminate between patients with prion disease (PrD) and…Asymmetric Orthostaic Myoclonus – A Case Series
Objective: To present the first case series of asymmetric orthostatic myoclnus and its reversibility along with the improvement of the underlying disease Background: Orthostatic myoclonus…In vivo evaluation of tau and amyloid pathology in Corticobasal Syndrome
Objective: To assess in vivo, with molecular imaging the brain distribution of tau aggregates ([18F]AV1451 PET) and β-amyloid depositions ([18F]AV45 PET) in patients with Corticobasal…Neuroticism and depression is associated with impulse control disorder in Parkinson’s disease: a controlled study
Objective: Cross-sectional assessment of personality trait, impulsivity, depression and anxiety collected prospectively in Parkinson’s disease (PD) with impulse control disorders (PD-ICD) compared to a matched…MANF protects dopamine neurons and locomotion defect from Neurotoxin/Human alpha-synuclein-induced progressive Parkinson’s disease models in C.elegans.
Objective: To study whether Mesencephalic astrocyte-derived neurotrophic factor (MANF) has beneficial effects in parkinson disease and its intracellular mechanisms. Background: The distinguishing feature of Parkinson’s…Decisional capacity for Goals of Care in Parkinson’s Disease with Cognitive Concerns
Objective: We sought to assess decisional capacity (DC) for Goals of Care (GOC) using the MacArthur Competence Assessment Tool (MacCAT) for Parkinson’s disease (PD) patients…Validation of Computerised Measures of Executive Functioning for use in Parkinson’s Disease Assessments.
Objective: i. To validate the use of a computerised finger tapping task as a screening measure for Executive Dysfunction (EF) in Parkinson’s Disease (PD), against…
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