MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2017 International Congress

    Levodopa responsiveness in Parkinson’s disease is significantly impaired in those with diabetes and increased vascular risk.

    N. Malek, M. Lawton, K. Grosset, N. Bajaj, R. Barker, Y. Ben-Shlomo, D. Burn, T. Foltynie, J. Hardy, H. Morris, N. Williams, N. Wood, D. Grosset (Ipswich, United Kingdom)

    Objective: To define variation in L-dopa response in recent onset PD. Background: L-Dopa responsiveness is a defining feature of Parkinson’s disease (PD), but the degree…
  • 2017 International Congress

    Effect of Droxidopa Treatment on Fear of Falling in Patients With Neurogenic Orthostatic Hypotension: Clinical Trial and “Real World” Results

    S. Kymes, C. François, G. Peng, G. Rowse, S. Isaacson (Deerfield, IL, USA)

    Objective: To assess the impact of droxidopa on fear of falling in patients with symptomatic neurogenic orthostatic hypotension (nOH) in 2 studies. Background: nOH results…
  • 2017 International Congress

    Motor stress elicits dystonia-like movements in a pharmacological mouse model for Rapid-Onset Dystonia-Parkinsonism (DYT12)

    L. Rauschenberger, J. Volkmann, C.W. Ip (Wuerzburg, Germany)

    Objective: To study if a mild stressful trigger by motor activity leads to development of dystonia-like movements in a pharmacological mouse model for DYT12. Background:…
  • 2017 International Congress

    Research on Relationship between Sensory Tricks of Cervical Dystonia and Function of Cerebral Cortex

    T. Li, Z. Liang, C. Song, L. Zhou, L. Jing (Dalian, China)

    Objective: To investigate demography of sensory tricks in cervical dystonia, to discuss relationship between sensory tricks and function of sensorimotor integration in supplementary motor area of…
  • 2017 International Congress

    Associations between Functional Networks and Temporal Discrimination Thresholds in Cervical Dystonia patients and their unaffected relatives

    S. Narasimham, V. Sundararajan, E. McGovern, B. Quinlivan, I. Beiser, R. Beck, S. Riordan, M. Hutchinson, R. Reilly (Dublin, Ireland)

    Objective: To investigate resting state functional networks across cervical dystonia patients and their unaffected relatives with and without abnormal temporal discrimination thresholds (TDTs) based on…
  • 2017 International Congress

    Treatment of back pain in patient with extensor truncal dystonia with lumbar radiofrequency ablation (RFA)

    S. Giles, N. Shneyder, J. Cupido, C. Brock, E. Gaitour (Jacksonville, FL, USA)

    Objective: Extensor truncal dystonia in majority of cases leads to significant low, mid back pain and discomfort secondary to muscle spasms and early degenerative spinal…
  • 2017 International Congress

    Disease modeling for Perry syndrome using patient induced pluripotent stem cells

    T. Mishima, T. Ishikawa, K. Imamura, T. Kondo, Y. Koshiba, R. Takahashi, J. Takahashi, A. Watanabe, N. Fujii, Y. Tsuboi, H. Inoue (Fukuoka, Japan)

    Objective: To develop a novel model of Perry syndrome using induced pluripotent stem cell (iPSC)-derived neurons. Background: Perry syndrome is a rare autosomal dominant disorder…
  • 2017 International Congress

    3D image as a complimentary assist in patients with Parkinson’s disease

    D. Khodjieva, N. Mansurova, N. Khaydarov (Bukhara, Uzbekistan)

    Objective:  To assist patients with PD to overcome the fear of stair ascent and descent with help of 3D effect staircase  Background: Since walking on…
  • 2017 International Congress

    Effect of object size and obstacle avoidance on of Reach-to-Grasp Actions in Individuals with Parkinson’s disease

    S. Khacharoen, J. Tretriluxana, P. Srivanitchapoom, A. Pisarnpong, T. Chandharohit (Nakhon Pathom, Thailand)

    Objective: To investigate the effect of object size and obstacle on reach-to-grasp (RTG) actions in individuals Parkinson's disease (PD). Background: Previous studies reported impairments of…
  • 2017 International Congress

    Double-blind, randomized, placebo-controlled, Phase III study (TOLEDO) to evaluate the efficacy of apomorphine subcutaneous infusion in reducing OFF time in Parkinson’s disease patients with motor fluctuations not well controlled on optimized conventional treatment

    R. Katzenschlager, W. Poewe, O. Rascol, C. Trenkwalder, G. Deuschl, R. Chaudhuri, T. Henriksen, T. van Laar, K. Spivey, S. Vel, A. Lees (Vienna, Austria)

    Objective: The TOLEDO Study (NCT02006121) is a prospective, randomized, multicenter, double-blind, Phase III trial undertaken to investigate the efficacy of apomorphine subcutaneous infusion (APO) compared…
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