AAV-mediated human alpha synuclein overexpression in the locus coeruleus (LC) leads to a neuronal loss in the nucleus ambiguus of mouse.
Objective: To investigate the impact and temporal aspects of the neuronal loss in the LC neurons induced by alpha-synucleinopathy Background: In the Braak staging model…Efficacy of Tozadenant in Animal Models of Non-Motor Symptoms of Parkinson’s Disease
Objective: Investigate the potential of tozadenant (TOZ) to alleviate the non-motor symptoms of Parkinson's disease using multiple animal models. Background: TOZ is an oral, selective…Long-term Effects of Subthalamic Nucleus Deep Brain Stimulation on Quality of Life, Non-motor and Motor Symptoms
Objective: To study the long-term effects of bilateral subthalamic deep brain stimulation (STN-DBS) on Quality of Life (QoL), motor, non-motor symptoms (NMS) in patients with…Lower education level is associated with greater disability from pain in Parkinson’s disease patients
Objective: The objective of the current study is to explore whether a relationship between the level of educational attainment and degree of disability from pain…[11C]PK11195 PET in Alzheimer’s disease and progressive supranuclear palsy: the NIMROD study
Objective: Here we test whether the intensity and regional distribution of neuro-inflammation differs between Alzheimer's disease (AD), Progressive Supranuclear Palsy (PSP) and controls; and whether neuro-inflammation…Gait and Cognition in Progressive Supranuclear Palsy: A Significant Association
Objective: In this study we explored the association between gait parameters and cognitive function of PSP. Background: Gait and cognition are interrelated in patients with…Extrapyramidal involvement in amyotrophic lateral sclerosis: results of a prospective population-based study
Objective: To assess frequency, clinical characteristics and functional neuroimaging correlates of parkinsonian signs in a population-based series of new-diagnosed amyotrophic lateral sclerosis (ALS) patients. Background:…Metabolomics study in a group of Parkinson’s disease patients from Northern India
Objective: To do (1) H NMR study in a group of Parkinson’s disease patients, disease controls, viz. multiple system atrophy (MSA) and progressive supra nuclear…Alien Limb Syndrome Induced by a Dopamine Agonist in a Patient with Parkinsonism and Agenesis of the Corpus Callosum
Objective: To examine the case of a patient with parkinsonism and agenesis of the corpus callosum whose alien limb phenomenology ceased after withdrawal from ropinirole.…A case of Dementia with Lewy Bodies Co-Occuring with Multiple Sclerosis
Objective: To describe a unique case of Dementia with Lewy bodies (DLB) co-occurrence with Multiple Sclerosis (MS) Background: Various movement disorders have been described in…
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