IGF-1 levels are associated with CSF pathology and executive dysfunction in de novo Parkinson’s disease patients
Objective: To investigate whether serum insulin-like growth factor-1 (IGF-1) is associated with clinical-neuropsychiatric, imaging and CSF markers of PD pathology in patients with early, drug-naïve…INFLUENCES OF GENDER, DEPRESSION AND DISEASE SEVERITY ON MoCA SUBSCORES IN PARKSINON’S DISEASE
Objective: We studied the causal relations between various external factors and MoCA subscores using Bayesian networks. Background: The MoCA is a standard screening test for…Genotype-phenotype correlations in Parkinson disease patients who carry mutations in the GBA gene.
Objective: To assess genotype-phenotype relationship between mild and severe GBA mutation carriers among patients with Parkinson's disease Background: Mutations in the Glucocerebrocidase gene (GBA) are…Association of the GBA T369M polymorphism with motor and cognitive symptoms in Parkinson’s disease
Objective: To determine whether the GBA polymorphism T369M is associated with earlier age of onset, lower cognitive performance, and more severe motor impairment in Parkinson's…Meta-analysis of the interaction between HLA-DRB1 and smoking with Parkinson’s disease
Objective: To investigate interactions between HLA-DRB1 rs660895 polymorphisms and smoking in PD using meta-analysis to pool data from three large population-based studies. Background: Inflammatory response…Motor and Nonmotor clinical phenotype in LRRK2 Parkinson’s disease patients: a Case-control study
Objective: Our study aimed to characterize and compare the clinical phenotype of LRRK2-PD patients with PD patients with no identified mutations. Background: The clinical phenotype…Perceptions of Fluctuation Treatment in Parkinson’s Disease Impact Suicidality
Objective: Our goal was to examine the relationship between suicidality and motor fluctuations in Parkinson’s disease (PD) patients. Background: On/off motor fluctuations in PD are…Changes in motor subtype designation of early Parkinson’s disease patients
Objective: To examine changes in the designation of motor subtypes in Parkinson's disease (PD) patients within five years of diagnosis. Background: Distinct motor subtypes of…Medication optimization in Parkinson’s disease patients with ON-state freezing using objective gait assessments
Objective: To determine whether objective gait assessments could guide therapeutic decision making in Parkinson’s disease (PD) patients reporting freezing of gait (FOG) in the levodopa-ON…Diplopia: An Interesting Complication of Dropped Head Syndrome
Objective: To describe an interesting case of new-onset diplopia due to loss of compensation for trochlear nerve palsy as a result of dropped head in…
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