Variation in Longevity Gene KLOTHO Associates with Measures of Resilience Against Parkinson’s Disease
Objective: We investigated whether carrying one copy of the protective haplotype “KL-VS” of the longevity gene KLOTHO is associated with better cognitive functioning and/or attenuated…Event-related potentials and mild cognitive impairment in Parkinson’s disease.
Objective: To measure N170, P3a/P3b peak amplitudes and latencies in PD with (PD-MCI) and without (PD-NC) mild cognitive impairment and to correlate them with clinical-demographic, neuropsychological and…Neurodegenerative biomarker abnormality frequency in idiopathic REM sleep behavior disorder
Objective: To describe the frequencies of neurodegenerative biomarker abnormalities in the adult Mayo Clinic iRBD prospective registry cohort. Background: The majority of patients with idiopathic…Parkinson’s disease in untreated Gaucher patients is associated with reduced glucosylsphingosine (Lyso-Gb1) serum levels
Objective: To assess the role of glycosphingolipids in increased risk of Parkinson's disease (PD) in patients with Gaucher disease (GD). Background: Patients with GD are…The therapeutic effect of MANF in the MPTP/MPP+-induced model of Parkinson’s disease
Objective: To observe therapeutic effect of MANF in the attenuation of neurotoxin MPTP/MPP+-induced model of Parkinson's disease Background: Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a…Parkinsonian Features in a Cohort of Gaucher’s Disease (GD) Patients and Relatives.
Objective: to investigate the prevalence and clinical features of parkinsonism in a cohort of 21 GD patients and their relatives. Background: GD is a lysosomal…Pure ATXN10 repeat expansion causes Parkinson’s disease
Objective: Clinical and genetic characterization of a multigenerational family with spinocerebellar ataxia type 10 (SCA10) and parkinsonism. Background: Pentanucleotide repeat expansions of ATTCT in intron…Short term effects of bilateral STN DBS on psychiatric profile in Parkinson’s disease
Objective: We intend to look into the effects of bilateral STN DBS on Psychiatric profile of Parkinson’s patients. Background: Parkinson’s disease is a well-known degenerative…Young Onset Parkinson’s Disease (YOPD): A different disease entity?
Objective: To study the clinical manifestations of YOPD and Late Onset Parkinson’s Disease (LOPD) patients Background: Parkinson’s disease (PD) is a neurodegenerative disease commonly affecting…Determinants of balance confidence and concern about falling in people with Parkinson’s disease
Objective: To identify factors that contribute to balance confidence and concern about falling in people with Parkinson’s disease (PD). Background: Reduced balance confidence and greater…
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