Effect of object size and obstacle avoidance on of Reach-to-Grasp Actions in Individuals with Parkinson’s disease
Objective: To investigate the effect of object size and obstacle on reach-to-grasp (RTG) actions in individuals Parkinson's disease (PD). Background: Previous studies reported impairments of…Double-blind, randomized, placebo-controlled, Phase III study (TOLEDO) to evaluate the efficacy of apomorphine subcutaneous infusion in reducing OFF time in Parkinson’s disease patients with motor fluctuations not well controlled on optimized conventional treatment
Objective: The TOLEDO Study (NCT02006121) is a prospective, randomized, multicenter, double-blind, Phase III trial undertaken to investigate the efficacy of apomorphine subcutaneous infusion (APO) compared…Disease severity is not predictive of the dose required for apomorphine sublingual film (APL-130277) to convert a patient with Parkinson’s disease(PD) from OFF to fully ON: Preliminary Results from a Phase III Study
Objective: To determine if baseline disease severity could be correlated to the effective dose of APL-130277 that was required to turn a patient with PD…Deep Learning in Objective Classification of Spontaneous Movement of Patients with Parkinson’s Disease Using Large-Scale Free-Living Sensor Data
Objective: Our goal was to classify spontaneous movement using a commercially available motion sensor in a clinically meaningful 3-/9-step discrete scale (SMS-3/SMS-9). Background: Brady-hypokinetic and dyskinetic…Deep brain stimulation in Parkinson’s disease: Outcome after more than nine years
Objective: The aim of this study is to examine the long-term effects of deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson’s disease…Early morning OFF problems are common in PD patients attending a routine clinical appointment
Objective: To characterize early morning OFF problems in consecutive PD patients attending a routine clinical appointment. Background: In PD patients with motor fluctuations, total daily…Programming of deep brain stimulators in Parkinson’s disease with early motor complications (EARLYSTIM-study)
Objective: Recently the EARLYSTIM study showed the superior effect of subthalamic stimulation to best medical treatment in Parkinson`s disease with early motor complications. Background: EARLYSTIM…Manual and Verbal guidance during the balance training based in virtual reality is essential for therapeutic results in people with Parkinson’s disease: a randomized clinical trial
Objective: To compare the effects of balance training in Virtual Reality (VR) supported by manual and verbal guidance (MVG) versus an identical training in absence…The effect of dance and Nordic Walking on balance, gait and motor function in Parkinson’s disease
Objective: To present two rehabilitation programs based on dance and Nordic Walking (NW) for patients with Parkinson’s disease (PD) and their effects. Background: Parkinson’s disease…Interactions between amyloid-β and microglial activation in Parkinson’s disease
Objective: To evaluate the relationship between microglial activation and amyloid-β deposition in the brain using positron emission tomography (PET) in Parkinson’s disease (PD) with normal…
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