Genotype-Phenotype correlations and expansion of the molecular spectrum of AP4M1-related Hereditary Spastic Paraplegia
Objective: To identify possible novel variants in a HSP family from Greece. Background: Autosomal recessive hereditary spastic paraplegia (HSP) due to AP4M1 mutations is a…Efficacy and safety of incobotulinumtoxinA (inco/A) for essential tremor using kinematics-guided clinical decision support: A randomized, double-blind, placebo-controlled trial
Objective: To demonstrate improvement of arm tremor severity and hand function with kinematics-guided inco/A therapy Background: Botulinum neurotoxin A (BoNT-A) therapy of debilitating tremor symptoms…Interim Results of an Ongoing Open-label Safety Study of ADS-5102 (amantadine hydrochloride) Extended-Release Capsules for Treatment of Levodopa-Induced Dyskinesia (LID) (EASE LID 2 Study)
Objective: Characterize the long-term safety and tolerability of 340 mg of ADS-5102 administered once daily at bedtime, for the treatment of LID in Parkinson’s disease…Exploring the neurophysiology of cervical dystonia using TMS-EEG
Objective: To probe cortical excitability and inhibition in primary motor cortex and supplementary motor area (SMA) in cervical dystonia Background: Cervical Dystonia (CD) is characterized…A kinematic analysis of finger tapping in dystonia
Objective: To perform a computerised analysis of finger tapping in patients with dystonia and healthy controls in order to develop a better understanding of the…Impaired Pain Processing in Functional Dystonia
Objective: Aim of the present study was to assess the sensory-discriminative and cognitive-emotional aspects of pain in patients with functional and idiopathic dystonia respectively assessing…Focused ultrasoud ventro-oral thalamotomy for musician’s dystonia
Objective: We investigated the effect of focused ultrasound Vo-thalamotomy for musician’s dystonia. Background: Lesioning of the ventro-oral nucleus (Vo-thalamotomy) is an effective treatment for musician’s…The Use of Atypical Antipsychotics in Depression and Anxiety may Unmask Parkinson’s Disease: A Retrospective Chart Review
Objective: Characterize the population with parkinsonism and exposure to antipsychotics who underwent dopamine transporter single-photon emission computed tomography (DATSPECT). Background: Atypical antipsychotics are used in …Falls characteristics of male and female patients with Parkinson’s disease (PD)
Objective: To compare Falls risk characteristics in male and female PD patients attending a multidisciplinary Movement disorders clinic. Background: Parkinson’s disease is commoner in males.…Death in patients with Parkinson’s disease – an observational study
Objective: We aimed to analyse the major cause and contributory reasons for death in patients with Parkinson’s disease (PD) who were known to our PD…
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