MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2017 International Congress

    Neuropsychiatric symptoms after bilateral stimulation in Parkinson’s disease: subthalamic nucleus versus globus pallidus internus.

    F. Fonoff, E. Fonoff, R. Machado, R. Cury, M.G. dos Santos, E. Barbosa (São Paulo, Brazil)

    Objective: The aim of this prospective study is to compare the effects of GPi and STN stimulation in PD patients on neuropsychiatric disorders and quality…
  • 2017 International Congress

    A registry study of multiple system atrophy in Hokkaido, Japan: HoRC-MSA Project 2014-16

    M. Matsushima, K. Sakushima, I. Yabe, Y. Kanatani, Y. Ito, T. Matsuoka, T. Katayama, H. Uesugi, K. Sako, A. Takei, M. Mori, S. Shimohama, N. Sato, S. Kikuchi, H. Sasaki (Sapporo, Japan)

    Objective: To investigate the epidemiological aspects of multiple system atrophy (MSA) in Hokkaido, Japan by using the Hokkaido Rare disease Consortium for MSA (HoRC-MSA). Background:…
  • 2017 International Congress

    Progression of milestones by clinical types in progressive supranuclear palsy: a longitudinal observational study of a cohort of patients with PSP/CBD (the JALPAC project)

    I. Aiba, T. Ikeuchi, H. Takigawa, T. Shimohata, T. Tokuda, M. Morita, O. Onodera, S. Murayama, K. Hasegawa, K. Nakashima (Nagoya, Japan)

    Objective: To elucidate the natural history of the PSP clinical phenotype Background: Recently, various clinical types of PSP have been reported, but details on their…
  • 2017 International Congress

    Diffusion-Weighted MRI discriminates Parkinson´s Disease from the Parkinsonian Variant of Multiple System Atrophy: a Meta-analysis

    S. Bajaj, F. Krismer, G. Wenning, W. Poewe, K. Seppi (Innsbruck, Austria)

    Objective: A systematic review and meta-analysis was performed to evaluate the diagnostic accuracy of DWI in the differential diagnosis of the parkinsonian variant of multiple…
  • 2017 International Congress

    Results of a Phase 1, Single Ascending Dose, Placebo-Controlled Study of ABBV-8E12 in Patients with Progressive Supranuclear Palsy and Phase 2 Study Design

    N. Mendonca, T. West, J. Braunstein, I. Fogelman, Y. Bordelon, I. Litvan, E. Roberson, H. Hu, P. Verghese, R. Bateman, H. Florian, D. Wang, D. Ryman, L. Gault, K. Budur, B. Rendenbach-Mueller, D. Kerwin, A. Boxer, D. Holtzman (Ludwigshafen, Germany)

    Objective: To present the results of a phase 1 study of ABBV-8E12 in subjects with Progressive Supranuclear Palsy (PSP) and design of a phase 2…
  • 2017 International Congress

    Lifetime exposure to estrogen and risk for progressive supranuclear palsy

    H.K. Park, I. Litvan, S. Ilango (Goyang-si, Republic of Korea)

    Objective: To investigate the protective effect of estrogen on progressive supranuclear palsy (PSP).   Background: Animal and human epidemiologic studies of Parkinson’s disease and Alzheimer’s dementia have…
  • 2017 International Congress

    Phenotypic Heterogeneity in PSP Variants – A Case Series

    S. BHADRAN, S. ABRAHAM, B. NATARAJAN, A. MEKKATTUKUNNEL, J. KRISHNAN, R. ISAAC, P.K. PAL (THRISSUR, India)

    Objective: To present the phenotypic heterogeneity we observed in 5 PSP variants. Background: Progressive supranuclear palsy (PSP) is a primary tauopathy characterised by progressive gait…
  • 2017 International Congress

    A Novel Model of Care for Advanced Parkinson’s Disease and Related Disorders: Interdisciplinary Home Visits

    J. Fleisher, W. Barbosa, M. Sweeney, S. Oyler, A. Lemen, A. Fazl, M. Ko, T. Meisel, N. Friede, G. Dacpano, R. Gilbert, A. Di Rocco, J. Chodosh (New York, NY, USA)

    Objective: To describe the structure and feasibility of an interdisciplinary home visit program (HVP) for homebound advanced Parkinson’s disease (PD) and related disorders. Background: As…
  • 2017 International Congress

    Patient-Reported Outcomes in a Prospective Real-World Study of Droxidopa for the Treatment of Neurogenic Orthostatic Hypotension

    S. Kymes, C. François, K. McLeod, A. Duhig, A. Ogbonnaya, A. Quillen, J. Cannon, C. Shibao, B. Yue, I. Biaggioni (Deerfield, IL, USA)

    Objective: To assess the effect of droxidopa treatment on function, depression, and health-related quality of life (HRQoL) in patients with neurogenic orthostatic hypotension (nOH). Background:…
  • 2017 International Congress

    Safety of Unilateral and Bilateral DBS implants in ET: Preliminary results from Product Surveillance Registry

    M. Schiess, S. Falowski, G. Plotkin, S. Palfi, T. Witt, E. Cuny, T. Theys, K. Martinez, R. Plunkett, Y. Temel, G. Johnson, T. Weaver, J. Krauss, P. Konrad (Houston, TX, USA)

    Objective: To compare the safety of unilateral  (Uni) to bilateral (Blt) DBS implants in Essential Tremor (ET).  Background: DBS is an effective therapy in reducing…
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