INTREPID: A Prospective, Double Blinded, Multicenter Randomized Controlled Trial Evaluating Deep Brain Stimulation with a New Multiple Source, Constant Current Rechargeable System in Parkinson’s disease
Objective: INTREPID is designed to assess the improvement in motor function and quality of life in patients with Parkinson’s disease (PD) following Deep Brain Stimulation…Neuroprotective role of Tinospora cordifolia in MPTP induced Parkinsonian mouse model
Objective: To evaluate the neuroprotective effect of Tinospora cordifolia aqueous extract (TCAE) in Parkinsonian mice. Background: Parkinson’s disease, an age related neurodegenerative disorder, is characterized…Comparison of virtual-reality-gaming and activity-based gait and balance training on gait, balance and quality of life in patients with Parkinson’s disease
Objective: Investigate and compare the effects of virtual-reality-gaming(VRG) and activity-based gait and balance training (AGBT) on gait and balance parameters (cadence(CD), stride length (SDL), step…Efficacy and safety of Rasagiline in treatment of gait disturbances in dementia with Lewy bodies
Objective: We aimed to investigate the efficacy and safety of rasagiline in addition to levodopa in patients with dementia with Lewy bodies (DLB). Background: Management…Patients experiencing peak-dose dyskinesia use re-distribution of involuntary movement amplitude throughout their body to minimize the functional impact of dyskinesia
Objective: To investigate the presence of a strategy in dyskinesia amplitude re-distribution enabling patients to perform motor tasks. Background: In Parkinson’s disease (PD), occurrence of…Global Improvement and Patient Satisfaction: Results from a Long-Term, Open-Label, Rollover Study of Valbenazine in Tardive Dyskinesia
Objective: To assess global improvement and patient satisfaction in participants with tardive dyskinesia (TD) who received long-term treatment with once-daily valbenazine (VBZ). Background: VBZ, approved…Incremental hourly burden of “OFF” episodes on patient quality of life and health resource use among patients with Parkinson’s disease: A Neurologist/Patient Real World Assessment in the US
Objective: To investigate the incremental hourly burden of “OFF” episodes on health resource utilization (HRU) and health- related- quality of life (HRQoL) from a real…A new distinct spastic ataxia with hypomyelination: Clinical, neuroimaging and molecular expression of NKX6-2 mutations
Objective: To identify the phenotypic, neuroimaging and genotype-phenotype expression of NKX6-2 mutations. Background: Despite advances in genetic testing a large number of hyopomyelinating disorders remain…A Case of Paraneoplastic Myoclonus Attributed to Non-Small Cell Lung Cancer
Objective: To describe a patient with papillary Non-Small Cell Lung Cancer (NSCLC) who developed acute and rapidly progressive myoclonus with prominent palatal involvement as a…Non-motor symptoms and alteration of brain networks in patients with blepharospasm and hemifacial spasm
Objective: To investigate the differences of non-motor symptoms and the alteration of intrinsic brain networks in patients with blepharospasm and hemifacial spam. Background: Blepharospasm (BSP)…
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