Depressive symptoms may predict the future development of freezing of gait in patients with Parkinson’s disease: Findings from a 5-year prospective study
Objective: To explore which symptoms contribute to the future development of freezing of gait (FOG) in Parkinson's disease (PD) patients without FOG. Background: Prospective studies…Weight loss is associated with rapid striatal dopaminergic degeneration in Parkinson’s disease
Objective: To investigate whether weight loss has a longitudinal association with striatal dopaminergic degeneration in Parkinson's disease (PD). Background: Weight loss in PD is associated…No differences in the total burden of non-motor symptoms between Parkinson’s disease and non-degenerative parkinsonism
Objective: To compare the total burden of non-motor symptoms between Parkinson's disease and non-degenerative parkinsonism and to study the possible dopaminergic background of these symptoms.…Stigma and communication in people with Parkinson’s disease (PPD)
Objective: To present results about stigma in PPD from a Parkinson’s Workshop. These are preliminary results in the path to address the main project question…Freezing of gait recognition in Parkinson’s disease: A subject independent objective method
Objective: In this study, we aim to build an automated-FoG-detector for subject-independent. After extracting enormously relevant features, we apply variance detection-techniques to identify-FoG-events. Background: Gait…Profiles of microRNA in cerebrospinal fluid could be potential biomarkers for identifying motor subtype of Parkinson’s disease
Objective: We investigated CSF miRNA expression in PD and control subjects. We also evaluated if specific miRNA were differently expressed according to motor subtype of…Nanoscale imaging reveals disorganization of the brain extracellular space in Lewy body-injected mice
Objective: To explore the brain extracellular space and its matrix at a nanometric scale in a context of α-synuclein-induced neurodegeneration. Background: The extracellular space (ECS)…Red cell distribution with levels in Parkinson’s disease patients
Objective: Parkinson’s Disease is a neurodegenerative disorder caused by oxidative stress, protein changes and mitochondrial disfunction. Lately, it has been suggested that inflammatory cytokine levels…Characterization of the preclinical model parkinQ311X
Objective: To characterize the preclinical model parkinQ311X. Because the PARK2-associated disease in humans is characterized by juvenile onset and slow progression, in order to clarify…Carrier Mediated Delivery System Bearing Dopamine for Effective Management of Parkinsonism
Objective: In the present investigation, amino acid coupled liposome bearing dopamine-HCl were prepared to deliver drug to the brain utilizing receptor-mediated transcytosis for effective management…
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