A metabolomic signature of treated and drug-naïve patients with Parkinson disease: A pilot study
Objective: The aim of our case–control study is to compare entire blood metabolomic profiles obtained from treated PD patients, de novo PD patients and controls,…Acoustic analysis and subjective vocal perception of Parkinson’s disease patients and healthy control and the relation to depression and quality of life
Objective: To assess the acoustic differences between PD patients and healthy control (HC), the participants' perception of their vocal characteristics and the relation of the…Rasagiline as Adjunctive Therapy Induced Impulse Control Disorders in Parkinson’s Disease
Objective: In recent years there are an increasing number of impulse control disorders (ICDs), such as pathologic gambling, hypersexuality, compulsive shopping, compulsive eating, punding and…Impact of postural stability estimation in HY scale. (Pull test Vs. limits of stability assessment)
Objective: Stability evaluation is of much value for staging the disease according to the Hoehn and Yahr (HY) scale. We propose to correlate a dynamic…Differences in the Unified Dyskinesia Rating Scale based on age, Parkinson´s Disease and Dyskinesias duration
Objective: To analyze the Unified Dyskinesia Rating Scale (UDysRS) scores on Historical, Objective parts and their differences based on age, Parkinson´s disease (PD) and dyskinesias…Specific active immunotherapy (SAIT) against alpha-synuclein with AFFITOPE® PD01A and PD03A: Results from the AFF009 phase I trial
Objective: Phase I study with AFFITOPE® PD01A and PD03A to assess safety and tolerability as well as immunogenicity of this approach in MSA patients. Background:…Relationship between non-motor symptom symptoms and clinical symptoms in Parkinson’s disease using “Non-Motor Symptom assessment scale for Parkinson’s disease”
Objective: We evaluated the relationship between non-motor symptoms and clinical signs in patients with Parkinson’s disease (PD). Background: Patients with Parkinson's disease (PD) manifest not…Intraoperative local field potential recordings from deep brain stimulation electrodes help predict efficacy of subthalamic nucleus stimulation in patients with Parkinson’s disease
Objective: Subthalamic nucleus (STN) deep brain stimulation(DBS) is an effective treatment for advanced Parkinson's disease (PD). Two electrophysiological techniques aid identification of the optimal target.…Polysomnographic data in Dementia with Lewy Bodies: Correlation with clinical features and comparison with other alfa-synucleinopathies
Objective: 1) Polysomnography (PSG) assessment of sleep in Dementia with Lewy Bodies (DLB). 2) Correlation between PSG data, fluctuations and hypersomnolence. 3) Comparison of PSG…Intrastriatal Fyn silencing as a gene therapy strategy to manage levodopa induced dyskinesia in a mice model of Parkinson’s disease
Objective: To genetically abrogate Fyn expression to reduce levodopa induced dyskinesia (LID) in the 6-OHDA mice model of Parkinson’s disease (PD), using intrastriatal-injected lentiviral (LV)…
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