Differences in the Unified Dyskinesia Rating Scale based on age, Parkinson´s Disease and Dyskinesias duration
Objective: To analyze the Unified Dyskinesia Rating Scale (UDysRS) scores on Historical, Objective parts and their differences based on age, Parkinson´s disease (PD) and dyskinesias…Specific active immunotherapy (SAIT) against alpha-synuclein with AFFITOPE® PD01A and PD03A: Results from the AFF009 phase I trial
Objective: Phase I study with AFFITOPE® PD01A and PD03A to assess safety and tolerability as well as immunogenicity of this approach in MSA patients. Background:…Relationship between non-motor symptom symptoms and clinical symptoms in Parkinson’s disease using “Non-Motor Symptom assessment scale for Parkinson’s disease”
Objective: We evaluated the relationship between non-motor symptoms and clinical signs in patients with Parkinson’s disease (PD). Background: Patients with Parkinson's disease (PD) manifest not…Intraoperative local field potential recordings from deep brain stimulation electrodes help predict efficacy of subthalamic nucleus stimulation in patients with Parkinson’s disease
Objective: Subthalamic nucleus (STN) deep brain stimulation(DBS) is an effective treatment for advanced Parkinson's disease (PD). Two electrophysiological techniques aid identification of the optimal target.…Polysomnographic data in Dementia with Lewy Bodies: Correlation with clinical features and comparison with other alfa-synucleinopathies
Objective: 1) Polysomnography (PSG) assessment of sleep in Dementia with Lewy Bodies (DLB). 2) Correlation between PSG data, fluctuations and hypersomnolence. 3) Comparison of PSG…Intrastriatal Fyn silencing as a gene therapy strategy to manage levodopa induced dyskinesia in a mice model of Parkinson’s disease
Objective: To genetically abrogate Fyn expression to reduce levodopa induced dyskinesia (LID) in the 6-OHDA mice model of Parkinson’s disease (PD), using intrastriatal-injected lentiviral (LV)…Propofol-induced acute dystonic reaction after orthopedic surgery in a young healthy woman
Objective: Background: Acute dystonic reactions (ADR) are well known adverse effects of dopamine receptor blocking agents, as antipsychotics or anti-emetics. Propofol-induced ADR, albeit yet described,…Asynchronous Consultation in Movement Disorders: The East Africa Hub
Objective: Improving education and care in movement disorders through telemedicine. Background: In 2012, the Movement Disorders Society launched a telemedicine project to enable professionals from…Epigenetic silencing in the humanized mouse model of Friedreich ataxia
Objective: To investigate if DNA hypermethylation of the abnormal FXN gene in Friedreich ataxia is present in disease-relevant tissues and if it is tissue-, repeat-,…Clinical and genetics characterization of patients with Myoclonus Dystonia Syndrome
Objective: To characterize clinically and genetically a series of 23 patients with myoclonus dystonia syndrome (MDS) and to explore the Unified Myoclonus Rating Scale (UMRS)…
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