- Efficacy of liquid sinemet on non-motor symptoms in Parkinson’s diseaseObjective: To investigate the short term effect of liquid sinemet on the non-motor symptoms of people with advanced Parkinson’ disease (PD) who experience complex motor…
- Effects of neural stem cell transplantation on the differentiation of dopaminergic neurons in the substantia nigra and changes to rotational behavior of Parkinson’s disease ratsObjective: To explore the effects of neural stem cells transplantation on the differentiation of substantia nigra dopaminergic neurons and on the rotational behavior in a…
- B lymphocytes may be protective in early Parkinson’s disease and in an animal model of dopaminergic cell deathObjective: To investigate B lymphocyte phenotype and function in human PD and in an animal model of disease. Background: The clinical course in Parkinson’s disease…
- Insulin degrading enzyme, a novel key protein against alpha-synuclein oligomers formation?Objective: The objective of this work is to study the interaction between α-synuclein and the insulin degrading enzyme in the pancreas of subjects with synucleinopathies.…
- Freezing of Gait in Parkinson’s Disease: Clinico-biochemical ObservationsObjective: We aimed to compare motor and non-motor functions, 2D-spatiotemporal gait parameters and serum oxidative markers including catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA)…
- Effects of Glial Heme Oxygenase-1 on Neuronal Alpha-Synuclein in the GFAP.HMOX1 Mouse Model of Parkinson’s DiseaseObjective: To determine whether astroglial HO-1 transduces environmental and endogenous stressors into patterns of neural damage which promote the toxicity of neuronal alpha-synuclein. Background: The…
- Classification of Dopaminergic-State and Motor Activity by Theta, Beta and Gamma Activity in Parkinson’s DiseaseObjective: To test whether machine learning algorithms are suitable to classify dopamine and behavioral states in Parkinson’s patients (PD). Background: While motor symptoms of PD…
- Evaluation of affective temperament and bipolarity among patients with Parkinson’ s diseaseObjective: To compare the bipolarity and affective temperament scores between patients with Parkinson’s Disease (PD) and healthy controls. Background: Mood disorders are the most common…
- Evaluation of impulsivity in Parkinson’ s diseaseObjective: To evaluate the impulsivity in patients with Parkinson’s Disease. Background: Parkinson’s disease (PD) is a chronic, neurodegenerative, progressive disease characterized with cardinal motor symptoms…
- Depression, apathy, fatigue in Parkinson with or without STN DBSObjective: To determine the prevalence of depression, evaluate the relationship between depression, apathy and fatigue, and the impact of STN DBS on the same symptoms.…
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