Parallel evaluation of mutant huntingtin and neurofilament light in Huntington’s disease
Objective: To assess cerebrospinal fluid (CSF) mutant Huntingtin (mHTT), and CSF and plasma neurofilament light (NfL) in Huntington’s disease (HD). Background: HD is a progressive…Exploration of insight competence in Huntington’s disease supplemental to a cognitive debriefing study for the FuRST2.0 rating scale
Objective: Evaluate insight of functional impairment in premanifest and early-manifest Huntington’s disease (HD). Background: Following the guidelines of the US Food and Drug Administration Clinical…Changes in brain network activation (BNA) in patients with fragile x-associated tremor/ataxia syndrome (FXTAS)
Objective: We aimed to assess the ability of Brain Network Activation (BNA) EEG analysis to differentiate between patients with fragile X-associated tremor/ataxia syndrome (FXTAS), Parkinson’s…Has patients affected by REM sleep Behavior Disorder a specific brain glucose metabolism pattern?
Objective: This study aimed at evaluating brain glucose metabolism in patients affected by REM sleep behavior disorders (RBD) compared to Parkinson’s Disease (PD), Lewy Body…Longitudinal alpha-synuclein in cerebrospinal fluid in early Parkinson’s disease, prodromal PD and healthy controls
Objective: To examine the longitudinal relationships between total alpha-synuclein (aSyn) changes in cerebrospinal fluid (CSF), clinical measures, and factors that may influence CSF aSyn in…Parkinson’s disease-related non-motor features as risk factors for post-operative delirium in spinal surgery
Objective: We investigated the association between PD-related NMSs and postoperative delirium in old people undergoing elective spinal surgery. Background: The clinical features of postoperative delirium…C-spine injury with progressive gait difficulty, drop foot, bizarre gait and serum positive stiff person syndrome: A case report
Objective: A complicated case presented with trauma history and insidious onset of stiff person syndrome. Background: Stiff person syndrome is a rare neurological disorder characterized…Reversible Extrapyramidal features as unusual presentation of central pontine myelinolysis: A case report
Objective: To be acquainted with the extrapyramidal symptoms developed during the course of central pontine myelinolysis. To emphasize the importance of neuroimaging in the diagnosis…A case of levodopa responsive rapid onset dystonia-parkinsonism
Objective: We describe and demonstrate by video a young man with rapid onset dystonia parkinsonism who has a robust response to levodopa. Background: Rapid onset…Methylphenidate in Progressive Supranuclear Palsy [PSP] – Old drug, New Indications?
Objective: To evaluate whether Methylphenidate can improve some symptoms of PSP. Background: PSP is a neurodegenerative disorder with limited therapeutic options. Methylphenidate[MPH] , a drug…
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