Decreased blood beta-Glucosidase activity and GBA mutations in Dystonia
Objective: To report on the observation of decreased levels of GCase in peripheral blood in patients presenting with dystonia without signs of parkinsonism. Background: Glucocerebrosidase…Striatum of the ouabain-induced pharmacological DYT12 mouse model is affected by structural and metabolic abnormalities
Objective: To study changes in neuronal morphology and neurotransmitter metabolism in the striatum of a pharmacological DYT12 mouse model after induction of a dystonic phenotype…Parkinson’s Disease Risk in Breast Cancer
Objective: Case report of two patients who developed symptoms of Parkinson’s disease after treatment with chemotherapy and radiation for breast cancer and to review the…Droxidopa and Midodrine Treatment Persistence in Patients with Orthostatic Hypotension
Objective: To determine the treatment persistence of droxidopa and midodrine in patients with orthostatic hypotension (OH) or neurogenic orthostatic hypotension (nOH) when medication cost was…Treating Huntington’s Disease using a holistic approach
Objective: Huntington’s disease (HD) is a fatal genetic disorder that causes the progressive breakdown of nerve cells in the brain. It deteriorates a person’s physical…On the hunt for a link between genetically confirmed Huntington’s disease and Amyotrophic Lateral Sclerosis
Objective: To characterise the clinical and pathologic findings of Huntington’s disease (HD) and coincident amyotrophic lateral sclerosis (ALS). Background: A 66 year old man presented…Evaluation of a driving questionnaire to facilitate awareness of issues that could compromise driving ability in a person with Parkinson’s disease
Objective: To evaluate the usefulness of a driving questionnaire data collection tool to assist in the ongoing monitoring and identification of issues that could compromise…Dopaminergic stem cells reside in the rostral migratory stream
Objective: To analyze if the adult rostral migratory stream (RMS) harbors neural stem cells with the potential to create dopaminergic neurons for the olfactory bulb…Recruitment of Minority populations with Parkinson’s disease at an Urban Hospital
Objective: To evaluate diagnostic disparities in Parkinson’s disease (PD) through recruitment of underrepresented minorities into a PD screening study. Background: African-Americans are less likely than…Cerebral and pulmonary thromboembolism in a patient with hyperhomocystinemia treated with high dose levodopa/carbidopa intestinal gel
Objective: We report a case that developed cerebral and pulmonary thromboembolism during 24-hour levodopa/carbidopa intestinal gel (LCIG) infusion. Background: LCIG is a therapeutic option in…
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