Efficacy of sublingual apomorphine film (APL-130277) for the treatment of OFF episodes in patients with Parkinson’s disease: Results from the Phase 3 double-blind, placebo-controlled trial
Objective: To evaluate the efficacy of APL-130277 (APL) in a double-blind, placebo-controlled trial. Background: OFF episodes are a common, disabling complication of Parkinson’s disease (PD)…Inhibition of HDAC4 attenuates rotenone-induced abnormal increase of α-synuclein levels and affects autophagic flux in human dopaminergic SH-SY5Y cells
Objective: To explore the effects of selective inhibition of HDAC4, on levels of α-syn and autophagy-related proteins in PD. To discuss the mechanism for the…Multi-modal retention in a phase III clinical trial in early Parkinson disease (STEADY-PD III)
Objective: To evaluate novel retention strategies in an ongoing phase 3 clinical trial in individuals with Parkinson disease (PD). Adequate participant retention is a significant…Longitudinal observational study on late onset Parkinson’s disease over a decade
Objective: 1. To analyse the outcome of Late onset Parkinson’s disease over ten year period. 2. To look for any relationship between Initial cognition to…Determinants of absence of dyskinesia in Parkinson’s disease patients with treatment beyond 10 years
Objective: This study aims to explore the determinants for absence of dyskinesia in patients with Parkinson’s disease (PD) based on a large cohort of Chinese…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.