Exploring the neural correlates of gait asymmetry in idiopathic REM Sleep Behaviour Disorder
Objective: Given the typical asymmetric onset of motor symptoms in PD, the current study sought to investigate whether patients with iRBD show evidence of asymmetric…Safinamide inhibition of in vivo glutamate release in a rat model of Parkinson’s Disease
Objective: To evaluate whether safinamide inhibits in vivo glutamate (Glu) release in a rodent model of Parkinson’s disease (PD), i.e. the 6-hydroxydopamine (6-OHDA) hemilesioned rat.…The Small Molecule Alpha-Synuclein Misfolding Inhibitor, NPT200-11, Produces Multiple Benefits in an Animal Model of Parkinson’s Disease
Objective: To evaluate effects of NPT200-11 on Parkinson’s disease (PD)-relevant outcomes including alpha-synuclein pathology, neurodegenerative markers and motor performance in transgenic mouse models of PD.…Effect of lidocaine injection into the external oblique muscle on camptocormia and the lateral slant posture in patient with Parkinson’s disease
Objective: Camptocormia (CC) is one of the abnormal posture of Parkinson's disease (PD) patients, described as a severe forward flexion of the trunk. In this…Efficacy and safety of safinamide as a levodopa adjunct in patients with parkinson disease and motor fluctuations: A systematic review of randomized controlled trials
Objective: To assess the efficacy and safety of safinamide as an add-on therapy to levodopa in Parkinson patients. Background: Long-term use of levodopa is associated…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.