Identification of gut microbial genes in Parkinson’s disease by shotgun metagenomic analysis
Objective: To carry out deep analysis on gut microbiome in patients with Parkinson’s disease (PD) and to evaluate the potential application for diagnosing PD patients…Lysosphingolipids accumulation in macrophage model of Gaucher disease
Objective: The aim of this study was to investigate if GCase deficiency in macrophage model of GD lead to lysosphingolipids accumulation. Background: Mutations in the…The Parkinson’s Families Project: A family-based study of early onset and familial Parkinson’s disease
Objective: The aim of this study is to identify new genetic variants that cause or predispose to Parkinson’s disease (PD). Our secondary aim is to…Further insights into excitatory-inhibitory balance of the primary motor cortex in Parkinson’s disease: A triple-pulse stimulation study
Objective: To characterize intracortical facilitation and inhibition of the primary motor cortex (M1) in Parkinson’s disease (PD) using transcranial magnetic stimulation (TMS). Background: Since introduction…Olfactory dysfunction, sleep disturbances, neuronal loss, and regional brain atrophy in an inducible mouse model of Alpha-Synucleinopathy
Objective: The objective of this work is to develop a unique mouse model of spreading α-synucleinopathy to accelerate the development of novel disease-modifying treatments for…
