Apathy in Parkinson’s disease is associated with abnormal alpha oscillatory behaviour during incentivized movement
Objective: To determine the relation between apathy and neural oscillations in Parkinson’s disease (PD). Background: Apathy in PD, characterized by lack of motivation, is often…Multisite Tissue and Biofluid Sampling for Alpha-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)
Objective: To characterize the distribution of alpha-synuclein (aSyn) pathology in multiple tissues and body fluids within the same Parkinson’s disease (PD) subjects and compared to…Serum glutamate is associated with the motor subtype of Parkinson’s disease
Objective: We aimed to study the concentration of glutamate in the serum of patients with Parkinson's disease (PD) and its connection with clinical variants of…PrP as a receptor of alpha-synuclein in the pancreas of patients with synucleinopathies
Objective: We have investigated whether the cellular prion protein interacts with alpha-synuclein in pancreatic cells of patients with synucleinopathies. Background: Neurodegenerative diseases such as Alzheimer’s…Microglial activation, white matter and hippocampal damage correlate with cognitive impairment in chronic cerebral hypoperfused and MPTP-lesioned mice
Objective: We hypothesize that cerebral hypoperfusion may influence the cognitive function of PD animal models. To investigate the effects of cerebral hypoperfusion and microangiopathy on…
