Identification of putative serum biomarkers for parkin-related Parkinson’s disease by metabolome analysis
Objective: Parkin is known as the causative gene of autosomal recessive familial Parkinson’s disease (parkin-PD). It remains unclear how parkin dysfunction associates with the dopaminergic…Bmal1 deficiency aggravates MPTP-induced dopaminergic cell death through promoting neuroinflammation
Objective: Bmal1 is one of the most important central clock genes of circadian rhythm. Circadian rhythm dysfunction is one of the non-motor symptoms in Parkinson’s…Antibodies to alpha-Synuclein in Parkinson disease
Objective: Alpha-synuclein (α-syn) plays a very important role in pathogenesis of Parkinson’s disease (PD). There are enough evidence of neuroinflammation in the brain tissue of…Peripheral Inflammatory Mediators in Parkinson’s Disease – A Potential Biomarker
Objective: i.To determine if post-translationally modified phosphorylated α-synuclein levels are altered in the peripheral blood of Parkinson’s disease (PD) patients compared to control subjects. ii.To…Prevalence and associations for depression in patients with Parkinson’s disease: A Sri Lankan experience
Objective: Estimate the prevalence of depression among patients with PD presenting to a tertiary neurology clinic in the premier healthcare institution in Sri Lanka Identify…
