Change of Cognition Functions after Subthalamic Nucleus-Deep Brain Stimulationin in Parkinson’s Disease
Objective: To explore the changes of cognitive function in Parkinson disease (PD) patients with deep brain stimulation (DBS) of the subthalamic nucleus (STN). Background: STN-DBS…Adult neurogenesis is impaired in pink1-/- zebrafish (Danio rerio)
Objective: To determine whether PINK1 deficiency impairs adult neurogenesis in a tractable vertebrate model of PINK1-related Parkinson's disease (PD). Background: PD is characterized by loss…Mitochondrial phenotype related to the A30P alpha-synuclein mutation as a patient-derived cellular model of Parkinson’s disease
Objective: Our study aims to perform detailed phenotyping of the A30P alpha-synuclein familial case of PD, allowing to identify underlying mechanisms of the disease that…A review of modifiers of Parkinsonism in the Leucine-rich repeat kinase 2 (LRRK2) population
Objective: To review and examine the most current identified modifiers of Parkinsonism in the LRRK2 population. Background: LRRK2 is a protein with multiple domains and…Higher Levels of Serum Uric Acid Associated with Motor & Non-Motor Symptoms in Early Parkinson’s Disease
Objective: Uric acid (UA) has been shown to be potentially neuroprotective in Parkinson's disease (PD), a progressive neurodegenerative disorder that is clinically characterised by motor…
