Amantadine extended release (Gocovri) reduces dyskinesia and bradykinesia: Evaluation of clinical response with the wearable PKG (Personal Kinetigraph) watch
Objective: To determine the effect of bedtime high-dose amantadine extended release (Gocovri) in 50 consecutive patients experiencing motor fluctuations and dyskinesia. Background: Amantadine extended release…The utility of electrophysiological tests in the differentiation of upper limb tremor in young-onset patients
Objective: To explore the diagnostic utility of neurophysiologic tests in young-onset patients who present primarily with upper limb action tremor. Background: In young-onset patients, isolated…Case series of Holmes tremor at the Clinical Hospital of State University of Campinas
Objective: To describe a case series of Holmes tremor (HT) from Movement Disorders Outpatient Clinic at the Clinical Hospital of State University of Campinas, from…Voluntary suppression of Parkinson’s tremor
Objective: To provide the first detailed systematic investigation of the phenomenon of voluntary tremor suppression in Parkinson’s disease (PD). Background: We have observed in the…Phenotypic variability of essential tremor based on the age at onset
Objective: To explore the distribution of the AAO of essential tremor based on mathematical modeling and ascertain differences in the clinical features of subgroups. Background:…Role of Sex on Cholinergic Activity and Attention in Parkinson’s disease
Objective: To determine whether cholinergic activity related to attention differs in males versus females in people with Parkinson’s disease (PwPD). Background: Although cholinergic activity is…The effects of sensory reward cues on risky decision making in Parkinson’s disease
Objective: To evaluate the effects of sensory reward cues on risky decision making in unmedicated and medicated Parkinson’s disease (PD). Background: Cue reactivity may play…Clinical predictors of screen-defined dementia in early Parkinson’s
Objective: Predicting early dementia in Parkinson’s disease (PD) has important implications for individual prognosis, designing clinical trials and targeting novel treatments, but there remains a…Exploring the relationship between motor impairment, vascular burden and cognition in Parkinson’s disease
Objective: To determine frequency and type of cognitive disorders in cross-sectional analysis of a Parkinson’s disease (PD) cohort, and explore its relations to motor symptoms,…FDG-PET and metabolomics in PD-associated GBA variants
Objective: To assess the clinical, cognitive, metabolic, and imaging phenotypes of PD patients carrying the variants p.E365K and p.T408M in the GBA gene (NM_000157.3). Background:…
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