Restless legs syndrome in Parkinson’s disease patients: a comparative study on prevalence, clinical features, motor and non-motor symptoms
Objective: We investigate the prevalence of restless legs syndrome in Parkinson’s disease patients and to identify associated clinical features, motor and non-motor symptoms. Background: Restless…Comorbid REM sleep behavior disorder and impulse control disorder symptoms in early parkinson’s disease: The PPMI cohort
Objective: To assess the prevalence of Impulse Control Disorder symptoms (ICD) in Parkinson's disease with probable REM sleep behavior disorder (i.e. RBD assessed by questionnaire,…Risk estimation in the years preceding diagnosis of Parkinson’s disease in the PREDICT-PD cohort
Objective: To test and refine the use of probability-based algorithms to identify individuals at high-risk of developing Parkinson’s disease (PD). Background: Neurodegeneration preceding a formal…Pharmacological modulation of lysosomal glucocerebrosidase activity in the Thy1-aSYN mouse model of Parkinson’s disease
Objective: To study the pharmacological modulation of glucocerebrosidase activity in the Thy1-aSYN mouse model of Parkinson's disease (PD). Background: PD is a complex neurodegenerative disorder…Reduced vesicular storage of catacholamines enhance MPTP-induced death of dopaminergic neurons in locus coeruleus and olfactory bulb
Objective: In this study, we employed heterozygous knockout (vmat2+/-) mice to investigate the influence of reduced vesicular storage of catacholamines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-impaired dopaminergic neurons…Unraveling gut microbiota in Parkinson’s disease and atypical parkinsonism
Objective: (1) To evaluate the differences in gut microbiota among Parkinson’s disease (PD), atypical parkinsonism (i.e. multiple system atrophy [MSA] and progressive supranuclear palsy [PSP])…Enhancing protein palmitoylation is protective in alpha-synuclein dependent cytotoxicity
Objective: To determine if enhancement of protein palmitoylation benefits alpha-synuclein (aS) dependent vesicular trafficking defects and cytotoxicity. Background: Recent studies suggest that vesicular trafficking defects…Cortical correlates of dual-task turning with and without freezing of gait
Objective: This study investigated the relationship between prefrontal cortex (PFC) activity and turning characteristics with and without a dual-task in in people with Parkinson’s disease…Erotophonophilia and severe impulse control disorder in a patient with Parkinson’s disease
Objective: N/A Background: Paraphilia a form of hyper sexuality is a rare complication of dopaminergic drugs used in the treatment of Parkinson's disease (PD). We…Depression and associated factors in nondemented Chinese patients with Parkinson’s disease
Objective: This study aimed to estimate the prevalence and identify potential risk factors influencing depression in 519 consecutive nondemented Chinese PD patients. Background: Depression is…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.