Development of a biomarker for Parkinson’s disease by measuring alpha-synuclein oligomers in cerebrospinal fluid with ultrasonication-induced amyloid fibril formation
Objective: To establish a new technique quantifying misfolded alpha-synuclein (αSyn) oligomers in the CSF and to investigate their clinical - pathological significances in Parkinson’s disease…Exercise to improve upper limb function in people with Parkinson’s disease: A systematic review
Objective: To review the effectiveness and describe the exercise parameters of interventions targeting upper limb (UL) function in people with PD. Background: Reduced fine hand…The effects of treadmill training augmented by virtual reality on postural control and freezing of gait in Parkinson’s disease
Objective: To investigate whether treadmill training with virtual reality is beneficial both for Parkinson’s disease patients with and without freezing of gait (FOG) to address…Efficacy of CVT-301 (levodopa inhalation powder) for treatment of OFF periods in Parkinson’s disease
Objective: Post-hoc analysis of subjects with Parkinson’s disease (PD) achieving > 30% reduction in UPDRS motor score (UPDRSIII) from pre- to post-dose over the first…Activities of Daily Living and Quality of Life in Patients with Advanced Parkinson’s Disease Who Are Treated with or Planning to Use Device-Aided Treatments
Objective: To correlate activities of daily living (ADL) and quality of life (QoL) in advanced Parkinson’s disease (APD) patients with ongoing or planned device-aided treatment…Bio-Electro Stimulation Therapy for the Treatment of Motor and Non-Motor Symptoms in Parkinson’s Disease
Objective: Design an experiment to assess tremor severity comparable to the current clinical standard using Shimmer3 sensors. Investigate collected data to see if BEST intervention…Final MDS-UPDRS, Part IV Results of the EASE LID 2 Study: Long Term, Open-Label Study of ADS-5102 for Dyskinesia in Parkinson’s disease (PD) patients
Objective: An objective of this study was to evaluate the long-term duration of ADS-5102 effect on dyskinesia as assessed by the Unified Parkinson’s Disease Rating…Intranasal delivery of insulin for the restoration of memory signaling in Alzheimer disease
Objective: Objective of this study is to develop delivery-system to overcome BBB by employing novel, non-invasive approach via nasal route. Background: Alzheimer's disease(AD), a form…Effects of Botulinum Toxin treatment for sialorrhea in patients with cerebral palsy
Objective: To evaluate the benefits of treatment of drooling with Botulinum Toxin Type A (AbobotulinumtoxinA) in patients with cerebral palsy. Background: Patients with cerebral palsy…A Randomized Trial of Deferiprone for Pantothenate Kinase-Associated Neurodegeneration
Objective: To investigate whether treatment with the iron-chelating drug deferiprone (DFP) has benefit in patients with pantothenate kinase-associated neurodegeneration (PKAN), the most common form of…
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