MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Downregulation of blood serum microRNA 29 family in patients with Parkinson’s disease

    YL. Tang, J. Wang (Shanghai, China)

    Objective: The aims of the present study were to profile the expression of microRNA29 family (miR-29s) in blood serum from patients with PD vs unaffected…
  • 2018 International Congress

    Association of GBA polymorphisms and mutations with dementia in Parkinson disease: A 7-year study of three population-based incident cohorts

    K. Lunde, J. Chung, I. Dalen, K. Pedersen, J. Linder, M. Domellöf, E. Elgh, A. Macleod, C. Tzoulis, J. Larsen, O. Tysnes, L. Forsgren, C. Counsell, G. Alves, J. Maple-Grødem (Stavanger, Norway)

    Objective: To study the effect of GBA variants on dementia in three deeply phenotyped population-based prospective cohorts of patients with incident Parkinson disease. Background: Dementia…
  • 2018 International Congress

    Molecular mechanisms of GCH1-associated Parkinson’s disease

    J. Terbeek, W. Vandenberghe (Leuven, Belgium)

    Objective: To unravel the molecular mechanisms by which loss of GCH1 function enhances the risk of Parkinson´s disease (PD). Background: Loss-of-function mutations in GCH1 are…
  • 2018 International Congress

    Exploring novel diffusion-derived biomarkers in Parkinson’s disease Freezing of Gait

    B. Bluett, E. Bayram, S. Banks, Z. Mari, K. Sreenivasan, X. Zhuang, Z. Yang, C. Bird, D. Cordes, I. Litvan, V. Mishra (Las Vegas, NV, USA)

    Objective: To explore the association between novel diffusion-derived structural imaging biomarkers and disease duration in Parkinson’s disease with freezing of gait (PD-FOG). Background: Increasing free-water…
  • 2018 International Congress

    STN DBS modulates cortical auditory processing in advanced Parkinson’s Disease; a MEG-study

    K. Valkonen, J. Mäkelä, K. Airaksinen, J. Nurminen, R. Kivisaari, E. Pekkonen (Helsinki, Finland)

    Objective: To find out how deep brain stimulation (DBS) impacts cortical auditory processing in advanced Parkinson's disease (PD) patients. Background: Motor symptoms of PD can…
  • 2018 International Congress

    Putaminal dopamine depletion in de novo Parkinson’s disease predicts future development of wearing-off

    S.J. Chung, Y. Lee, J.S. Oh, J.S. Kim, P.H. Lee, Y.H. Sohn (Goyang, Republic of Korea)

    Objective: The present study aimed to investigate whether the level of presynaptic dopamine neuronal loss predicts future development of wearing-off in de novo Parkinson’s disease.…
  • 2018 International Congress

    Optimization of deep brain stimulation in STN among patients with Parkinson’s disease using a novel EEG-based tool

    D. Sand, Z. Peremen, D. Haor, S. Israeli-Korn, D. Arkadir, M. Abu Snineh, Z. Israel, S. Hassin-Baer, R. Eitan, H. Bergman, A. Geva (Jerusalem and Herzlia, Israel)

    Objective: The current study aims to develop an innovative method for objective differentiation between the locations of the four DBS contacts in the various parts…
  • 2018 International Congress

    Behavior and PET Imaging Study in Parkinsonian Rat Models Induced by Injection of 6-OHDA in Medial Forebrain Bundle

    W. Xian, Q. Guo, L. Jiang, Z. Pei, L. Chen (Guangzhou, China)

    Objective: To employ behavioral test, positron emission tomography (PET) imaging and immunohistochemical staining to assess the changes of brain function and dopaminergic system in rat…
  • 2018 International Congress

    Motor cortical inhibitory and facilitatory circuit interactions in Parkinson’s disease

    J. Saravanamuttu, N. Radhu, K. Udupa, C. Gunraj, J. Baarbé, R. Chen (Toronto, ON, Canada)

    Objective: To determine how intracortical circuits interact with one another in Parkinson’s disease. Background: Using transcranial magnetic stimulation (TMS), previous work has established that motor…
  • 2018 International Congress

    The difference in cerebellar blood flow reduction in multiple system atrophy and Parkinson’s disease

    N. Murakami, W. Sako, S. Haji, Y. Izumi, R. Kaji (Tokushima, Japan)

    Objective: The aim of this study is to determine if cerebral blood flow (CBF) reduction in the cerebellum could be a tool for differential diagnosis…
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