Return to automaticity: cortical activity during gait in Parkinson’s disease
Objective: This study investigated pre-frontal cortex (PFC) activation while walking in older adults and people with Parkinson’s disease (PD). We specifically examined 1) PFC activation…Neuroprotective effect of exogenous melatonin on apoptosis of neuroadernergic neurons in a rat model of Parkinson’s disease
Objective: To investigate melatonin therapeutic potential effects in Parkinson’s disease. Background: Sleep disorders constitute major nonmotor features of Parkinson’s disease (PD) that have a substantial…Characterization of the gastrointestinal dysfunction in mice overexpressing the human mutation (A53T) of alpha-synuclein
Objective: The aim of this study was to determine if mice overexpressing the human mutation of alpha-synuclein develop gastrointestinal (GI) dysfunction, and to understand the…Clinical subtypes of Parkinson’s disease based on nonmotor symptoms: A cluster analysis
Objective: To classify patients with early Parkinson's disease based on nonmotor symptoms using a data-driven approach. Background: Heterogeneity of Parkinson’s disease provides the basis for…Improvement of Levodopa-Responsive Chronic Pain after STN-DBS in Parkinson’s disease
Objective: To illustrate an example of an improvement in chronic pain, following bilateral subthalamic nuclei (STN) deep brain stimulation (DBS) surgery in a Parkinson’s disease…Smooth muscle dysfunction in the gastrointestinal system in the 6-OHDA model of Parkinson´s Disease
Objective: To explore the connection between the central dopamine system and the autonomous nervous system in GI dysfunction in PD, using animal models. Background: Gastrointestinal…Safinamide and Rasagiline effect on motor fluctuation, sleep quality and daytime sleepiness in Parkinson’s Disease: A validated questionnaires study
Objective: This is an observational study aimed at evaluating the effect of Safinamide and Rasagiline on motor fluctuations, subjective sleep and daytime sleepiness in Parkinson’s…Clinical heterogeneity of excessive daytime sleepiness in Parkinson’s disease
Objective: To examine reasons and associated clinical features of excessive daytime sleepiness (EDS) in patients with Parkinson’s disease (PD). Background: Patients with EDS can divided…Vowel characteristics associated with Parkinson’s disease in Cantonese
Objective: Dopaminergic treatment has been reported to help motor problem associated with Parkinson's disease (PD), but not speech motor. The current study examined vowel articulation…The validity of the Arabic King’s PD Pain Scale in people with Parkinson’s disease
Objective: This study aimed to examine the concurrent validity of Arabic translated version of the King's PD Pain Scale (KPPS) in people with Parkinson’s disease…
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