MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Evaluation of Parkinson’s Disease Psychosis Requires Structured Questioning of Patients and Caregivers

    P. Schmidt, F. Cubillos, A. Diaz, P. Wiener, S. Metz, N. Romero, C. Andersson, S. Andes, D. Fredericks, A. Shim (Miami, FL, USA)

    Objective: To determine the relationship between the patient and caregiver experience of the psychotic features of Parkinson's disease psychosis (PDP) reported to call center healthcare…
  • 2018 International Congress

    What can we learn from fMRI capture of visual hallucinations in Parkinson’s disease?

    K. Dujardin, D. Roman, G. Baille, D. Pins, S. Lefebvre, C. Delmaire, L. Defebvre, R. Jardri (Lille, France)

    Objective: To describe the patterns of brain functional changes when visual hallucinations (VH) occur in patients with Parkinson's disease (PD). Background: ​With disease progression, PD…
  • 2018 International Congress

    A Psychometric Analysis of the MDS UPDRS-II and III in Early Parkinson’s disease: Do the Numbers Add Up?

    A. Regnault, B. Boroodjerdi, J. Meunier, M. Bani, S. Cano (Lyon, France)

    Objective: Our objective was to explore the psychometric evidence for the use of the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) part II…
  • 2018 International Congress

    A German-Austrian multicenter, non-interventional, prospective study for the treatment with abobotulinumtoxinA injections in naïve and previously treated patients suffering from cervical dystonia

    W. Jost, A. Schramm, M. Müngersdorf, A. Stenner, P. Schwingenschuh, P. Maisonobe, M. Koch, B. Haslinger (Wolfach, Germany)

    Objective: In this prospective, multicenter, non-interventional study (NCT01840462) the primary objective was effectiveness of abobotulinumtoxinA in BoNT treatment-naïve and previously treated subjects after two injection…
  • 2018 International Congress

    Safinamide in Parkinson’s disease

    G. Martí-Andrés, R. Jiménez-Bolaños, J. Arbelo-González, J. Pagonabarraga-Mora, C. Duran-Herrera, M. Carmona-Abellán, R. Luquin-Puido (Pamplona, Spain)

    Objective: To evaluate clinical effects, safety and tolerability of safinamide add-on levodopa in Parkinson’s disease (PD) patients. Background: Safinamide is a recently approved adjunctive treatment…
  • 2018 International Congress

    Open-label extension (OLE) of a multiple ascending dose (MAD) study of BIIB092 in participants with PSP: Safety analysis

    T. Dam, L. Zhang, I. Qureshi, M. Grundman, G. Tirucherai, C. Bechtold, M. Ahlijanian, L. Golbe, L. Honig, S. Isaacson, M. Grossman, N. McFarland, I. Litvan, D. Geldmacher, T. Xie, Y. Bordelon, P. Tuite, P. O’Suilleabhain, T. Zesiewicz, B. Han, A. Boxer (Cambridge, MA, USA)

    Objective: To assess safety of BIIB092 in participants with progressive supranuclear palsy (PSP) in an OLE of a MAD study. Background: BIIB092 is a humanized…
  • 2018 International Congress

    Cognitive effects of SIRT6 overexpression: Emerging role of astrocytes

    N. Lev, Y. Barhum (Kfar Saba, Israel)

    Objective: The aim of this work was to elucidate the effect of SIRT6 overexpression on cognition. Background: Recent evidence show that astrocytes are important for higher brain…
  • 2018 International Congress

    Tardive Myoclonus: A Case Report

    S. Gazioglu, F. Civil Arslan, V. Altunayoglu Cakmak, M. Korucuk, M. Ozmenoglu (Trabzon, Turkey)

    Objective: To report a patient with late-onset myoclonus after treatment with antipsychotic drugs which is a rare variant of tardive movement disorders. Background: The use…
  • 2018 International Congress

    Effects of PGE inhibition on Striatal Neuroinflammation in 6-OHDA lesion

    T. Adu, M. Mabandla (Durban, South Africa)

    Objective: In this study, we investigated the role of prostaglandin E2 inhibition, pro-inflammatory cytokine concentration and microglial activation in a Parkinsonian rat Background: Neuro-inflammation plays…
  • 2018 International Congress

    Educating Movement Disorders through a web based counselling service in Mauritius

    M. Busgopaul (Port Louis, Mauritius)

    Objective: The provision of solutions and relevant information to the general public and mostly to young people is the way forward to help the elderly…
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