Effective Tools for Mild Cognitive Impairment Level I Criteria of Movement Disorder Society: Utility of Screening Tests and Their Interconversion
Objective: Our primary aim was to test the utility of the universally accepted screening tests for detecting mild cognitive impairment (MCI) in patients with Parkinson’s…The relationship between asymmetric dopamine loss and cognition in early Parkinson’s disease patients from PPMI study
Objective: To explore the role of motor asymmetry on cognition in early stage Parkinson’s disease (PD). Background: PD is characterized by asymmetric motor onset which…Agreement Between Patients and Informants on the Penn Parkinson’s Daily Activity Questionnaire
Objective: To assess agreement between Parkinson’s disease (PD) patients (PT) and knowledgeable informants (KI) on the Penn Parkinson’s Daily Activities Questionnaire-15 (PDAQ-15). To explore conditions…Effect of deep brain stimulation on clinical outcome in Parkinson’s disease patients with different genetic status
Objective: The aim of this study was to evaluate the effect of the genetic status on the clinical outcome of PD patients undergoing DBS. Background:…Resistance to Parkinson’s disease among LRRK2 mutation carriers is associated with higher plasma levels of urate but not its purine precursors
Objective: To determine whether plasma purine concentrations differ between people with Parkinson's disease (PD) and matched controls among carriers of pathogenic mutations in Leucine-Rich Repeat…Nurr1 gene: A new research target for Parkinson’s disease
Objective: The objective of our study is to determine if Nurr1 gene, a transcription factor essential for dopamine (DA) neuron development and survival, is a…Polymorphisms of glutamatergic system genes are associated with levodopa-induced dyskinesia in Parkinson’s disease
Objective: We aimed to study the association between glutamatergic system gene polymorphisms (SLC1A2 – gene, coding excitatory acids transporter, and GRIN2A gene, coding a subunit…Genome-wide association studies of motor and cognitive progression in Parkinson’s disease
Objective: Motor and cognitive progression in Parkinson’s is heterogeneous. Our aim is to identify single nucleotide polymorphisms (SNPs) associated with disease progression. Background: Rare genetic…Daughter’s ataxia reveals father’s genetic Parkinsonism. The first reported case of Spinocerebellar ataxia -15 presenting with levodopa responsive hemi Parkinsonism
Objective: A 38 year old Australian florist of Anglo-Celtic origin described two years of difficulty using his right hand with associated sensory disturbance attributed initially…Substantia Nigra Echogenicity Associated with Clinical Subtypes of Parkinson’s Disease
Objective: We classified Parkinson’s disease (PD) patients into different subtypes and evaluated the correlation between the substantia nigra (SN) echogenicity and disease progression. Background: It…
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