Classifying carriers of the G2019S mutation in the LRRK2 gene using MRI radiomics analysis
Objective: To use radiomics approach based on conventional MRI to classify carriers of LRRK2 mutation among non-manifesting first degree relatives of patients with PD. Background:…Gender Differences in Parkinson’s disease: Transcranial Magnetics Stimulation Study of Newly Diagnosed Drug-Naïve PD Patients
Objective: In early Parkinson’s disease (PD), functional changes may be detected in primary motor cortex (M1) using transcranial magnetic stimulation (TMS). We hypothesised that, if…Listen to the heart: Do loud vagal rhythms disharmonize the autonomic symphony in Parkinson’s disease patients with the LRRK2 mutation?
Objective: Assessment of cardiac autonomic function through standard and novel features of heart rate variability (HRV) in individuals who carry the G2019S mutation in the…Asymmetric olfactory deficit in H&Y stage-1 early onset Parkinson’s disease
Objective: To determine if the olfactory deficit in the early-stage Parkinson’s disease (PD) is asymmetric between the two hemispheres ipsilateral and contralateral to the onset…Evaluation of pain in Parkinson’s disease
Objective: To determine the prevalence of pain, types and characteristics of pain and the effect of pain on depression and daily living activities in early…Proteomic analysis of tear-fluid reveals disease-specific patterns in patients with Parkinson’s Disease
Objective: In this study, we set out to analyse changes of tear fluid (TF) proteome in Parkinson's Disease (PD) patients compared to age-matched controls (AMC)…Clinical differences between Parkinson’s disease motor phenotypes. Results from the COPPADIS Study Cohort
Objective: To describe the prevalence of different motor phenotypes in a large cohort of Parkinson´s disease (PD) patients and to analyze their clinical features in…Preliminary Study of Depression in Parkinson’s Disease with Diffusion Tensor Imaging
Objective: To explore the relationship between cognitive impairment in Parkinson’s Disease(PD) and the microstructure changes of brain region of interest(ROI) in diffusion tensor imaging(DTI). Background:…Impact of injection guidance techniques on the efficacy and safety of incobotulinumtoxinA for sialorrhea
Objective: SIAXI (NCT02091739), a pivotal double-blind, randomised, placebo-controlled study with an extension period (EP), assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U…Validation of a patient/caregiver questionnaire to evaluate nocturnal hypokinesia in Parkinson’s disease
Objective: To develop and validate a novel questionnaire to assess various aspects related to problems experienced by PD patients when turning in or getting out…
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