Apathy in Parkinson’s disease is associated with REM sleep behavior disorder
Objective: To assess apathy and its relationship with cognitive functions in PD patients with and without Rapid Eye Movement Sleep Behavior Disorder (RBD). Background: Apathy…Gut microbiota geography in Parkinson’s disease in the world
Objective: The 16 rRNA analysis and the shotgun metagenome analysis in our cohort were compared with 5 previous reports by others. Background: In PD patients,…The subthalamic stimulation inhibit bladder contraction by modulating local field potential and monoamine in the medial prefrontal cortex
Objective: We aimed to clarify the changes in neuronal activity (local field potential and levels of monoamine) of mPFC induced by STN-DBS with relation to…Levodopa-induced dyskinesia in Parkinson’s disease: Sleep matters
Objective: To investigate the relationship between slow wave activity (SWA) of non-rapid eye movement (NREM) sleep, which underlies adjustment of cortical excitability, and levodopa-induced dyskinesias…Experimental rotenone model
Objective: To evaluat rotene model of parkinsonian syndrome in rats. Background: Rotenone is of highly lipophilic substances that can freely enter hematoencephalic barrier through and…T lymphocytes in Parkinson’s disease pathogenesis and therapy: A systematic review
Objective: A systematic literature review was conducted to synthesize the current state of knowledge on the role of T lymphocytes in Parkinson’s disease (PD) pathology…Interaction of TDP-43 with IAPP in pancreatic beta cells of patients with sinucleinopathies
Objective: We have investigated whether deposits of phosphorylated TDP-43 might be present in pancreatic tissue of patients with synucleinopathies. Background: The TAR DNA binding protein…A post-mortem and in vivo study of neuroinflammation and Toll like-receptors in Parkinson’s disease
Objective: To investigate inflammatory change and Toll-like receptor (TLR) expression in human post-mortem Parkinson’s disease (PD) brains and to test the efficacy of TLR-blocking agents…Natural occurring antibodies reduce aggregation of α-synuclein
Objective: We tested naturally occurring antibodies (nAbs) against α-synuclein both in vitro as well as in HEK293T cells to determine binding, cell viability and capacity…Patients with Parkinson’s disease and psychosis have altered structural connectivity of the executive and visual networks
Objective: To analyze the integrity of visual and executive network of patients with Parkinson’s disease (PD) with psychosis (PD-P) and those without psychosis (PD-NP) and…
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