Availability of levodopa and clinicopathological features of patients with multiple system atrophy
Objective: To investigate the availability of levodopa for pathologically confirmed multiple system atrophy (MSA) patients and determine the clinicopathological features of levodopa responders with MSA.…Gray matter atrophy in Parkinson’s disease and freezing of gait assessed using surface-based algorithm – results of an open, longitudinal, single-centre study
Objective: The subsequent open, longitudinal study was performed to test whether grey matter (GM) atrophy and FOG severity changes over time and whether there is…The impact of HIV on the severity and course of Parkinson’s disease: a clinical case
Objective: About 12 million people in the world suffer from Parkinson's disease (PD), and 36.9 million suffer from HIV. The proportion of people with HIV…Modulation of cerebellar and basal ganglia loops affects vestibular processing in Parkinson’s disease
Objective: To investigate physiology of impaired balance control in Parkinson’s Disease and its modulation by deep brain stimulation Background: Postural instability leading to falls is…Utility of Eye Movement Abnormalities in Differentiating Neurodegenerative versus non-Neurodegenerative Parkinsonism
Objective: To evaluate eye movement abnormalities in patients with neurodegenerative versus non-neurodegenerative parkinsonism. Background: Clinical distinction between neurodegenerative and non-neurodegenerative parkinsonism can be difficult[1]. Eye…High repressive activity of olive extracts on the cell line model of Parkinson disease against ROS induction
Objective: Neurodegenerative diseases including Parkinson’s disease (PD) mostly accompany with induction of high ROS in neuronal cells. It is believed that unusual level of ROS…Blood brain barrier dysfunction cause idiopathic adult onset ventriculomegaly?
Objective: Our hypothesis is BBB disruption causes idiopathic adult onset ventriculomegaly (IAOV) also, astrocyte specific mitochondrial dysfunction is associated with BBB damage. Background: The cause…Deciphering Corticobasal Syndrome: are clinical features and FDG-PET imaging capable of predicting amiloyd status?
Objective: The present study aimed at establishing clinical and brain functional patterns at FDG-PET that could distinguish Corticobasal Syndrome(CBS) variants due to AD from Tau pathology based on Pittsburgh Compound…Aberrant structural connectivity of the executive network in Progressive Supranuclear Palsy
Objective: To ascertain the structural connectivity of the executive network in progressive supranuclear palsy (PSP) using probabilistic tractography. Background: Cognitive deficits are highly prevalent in…Pharmacokinetics of ABBV-951 Following 24-Hour Continuous Subcutaneous Infusion to Arm, Abdomen and Thigh
Objective: Characterize levodopa pharmacokinetics (PK) and safety/tolerability of ABBV-951 in healthy volunteers at 3 different subcutaneous (SC) infusion sites: Arm, Abdomen and Thigh Background: As…
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