Depression in Parkinson’s diseaese: Experience of the neurology department in Mohammed VI third level university hospital
Objective: The objectives of this study are to evaluate the frequency of depression in our Parkinson's disease patients, to describe the relationship of depression to…Acute, contact-dependent behavioral changes in Parkinson disease (PD) patients during monopolar contact review of subthalamic deep brain stimulation (DBS) using directional leads
Objective: To describe distinctive acute behavioral changes that occurred during monopolar review in PD patients implanted with DBS directional leads, operated consecutively over 12 months.…Functional exam findings in Lewy Body Disease
Objective: Case study to review functional exam findings in an abnormal Dopaminergic transporter scan positive Lewy body dementia patient. Background: Patient presented with known Parkinson’s…Genetic study of patients with Parkinson’s disease subjected to second line therapies
Objective: Parkinson's disease (PD) is a neurodegenerative disorder characterized by remarkable phenotypic variability. Accumulated evidence points that the manifestation of PD clinical signs might be…LRP10 variants and Parkinson’s disease in the Chinese population
Objective: LRP10 variants have recently been identified in individuals with familial Parkinson's disease (PD) and dementia with Lewy bodies. We aim to investigate if any…Mechanism-based classification in PD cohorts
Objective: To stratify Parkinson’s disease (PD) patients based on key molecular mechanisms by using a genomic-based approach. Background: PD is a complex neurodegenerative disease involving…Alpha-synuclein promoter (SNCA-Rep1) polymorphism is associated with non-motor symptoms in early Parkinson’s disease
Objective: We sought to investigate the relationship between SNCA Rep1 allele length and NMS in PD. Background: Associations between the alpha-synuclein gene (SNCA) promoter region…Novel p.Pro193Arg missense mutation in ABCD1-gene associated with phenotype of ALD/AMN: a case report
Objective: To describe a novel mutation p.Pro193Arg of the ABCD1-Gene in a patient presenting with clinical phenotype of Adrenomyeloneuropathy (AMN). Background: Adrenoleukodystrophy comprises progressive neurologic…The longevity gene Klotho and its CSF protein profiles as modifier for Parkinson´s disease in a longitudinal study
Objective: Our objective was to evaluate phenotype modifying effects of variants in longevity genes in PD. Background: Parkinson´s disease (PD) has a large phenotypic variability,…Temporal Emergence of Symptoms and Functional Impairments in Patients With Pantothenate Kinase-Associated Neurodegeneration (PKAN)
Objective: To describe the temporal emergence of PKAN symptoms and functional impairments across the spectrum of PKAN severity. Background: PKAN, an autosomal recessive, progressive neurodegenerative…
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