CHCHD2 maintains the MICOS and inhibits PINK1/Parkin mediated mitophagy in an experimental model of Parkinson’s disease
Objective: To illustrate the mechanism of CHCHD2 in regulating MICOS and mitophagy in Parkinson's disease.To illustrate the mechanism of CHCHD2 in regulating MICOS and mitophagy…The impact of medication and deep brain stimulation on visuo-motor coordination in Parkinson’s disease
Objective: The results presented herein are part of a larger study looking at the impact of medication and deep brain stimulation (DBS) on voluntary and…Long-term adherence with wearing a multi-sensor watch in the Personalized Parkinson Project
Objective: We assessed long-term participant engagement with a multi-sensor watch for continuous daily life monitoring among people with Parkinson’s disease. Background: Wearable sensors can potentially…Incidence of drooling in Parkinson’s Disease and Impact on Quality of Life
Objective: The project aimed to determine the frequency and severity of drooling in the Parkinson’s Disease (PD) population in Cardiff & the Vale Health-board through…Monitoring Parkinson’s disease symptoms during daily life: A feasibility study
Objective: This study explores the feasibility of a newly developed multimodal monitoring system, which aims to measure PD symptoms during daily life by combining wearable…Ocular Motor Dysfunction as the Predictable Milestone of Life Prognosis in Progressive Supranuclear Palsy
Objective: The purpose of this study was to identify which symptoms predict the life prognosis in progressive supranuclear palsy (PSP). Background: Patients with PSP are…Biomarkers of the Level of Cognitive Impairment (CI) in patients with Parkinson’s Disease (PD): MRS study
Objective: The concentrations of NAA, Cr, mIns, and Glx are identified as putative neurochemical markers of CI in patients with PD. Background: On the basis…Beneficial and protective effects of Terminalia chebula in a murine model of Parkinson’s disease
Objective: Present study was designed to investigate whether Terminalia chebula (TC) extract would prevent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced neurotoxicity in male Wistar rats. Background: Parkinson's disease (PD)…Corneal confocal microscopy: An imaging biomarker of neurodegeneration in Parkinson’s disease
Objective: The aim of the study is to investigate whether corneal confocal microscopy (CCM) can be used as a rapid, reliable, automated and non-invasive method…Automated Metabolic Pattern Analysis in the Differential Diagnosis of Parkinsonism in a Swedish Cohort
Objective: To assess the accuracy of an automated, disease-specific, pattern model to distinguish among PD, MSA and PSP, in comparison with the final clinical diagnosis.…
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