Interleaving stimulation in Parkinson’s disease: interesting to whom?
Objective: Overview our patients’ experience with ILS and explore clinical scenarios in which ILS should be considered when programming DBS in PD patients. Background: Interleaving…Functional Limits of Stability and Standing Balance in people with and without Freezing of Gait
Objective: To investigate whether Freezing of Gait (FoG) impacts functional Limits of Stability (fLoS) and postural sway during quiet stance and dynamic balance in a…Skin in the game: Small fiber neuropathy in Parkinson’s disease and atypical parkinsonisms.
Objective: The aim of our study was to compare somatic and autonomic small fiber density, through skin biopsy, in Parkinson's disease (PD) and atypical parkinsonisms…Association between transfer activities and health-related quality of life in patients with Parkinson’s disease
Objective: To investigate the association between health-related quality of life (HRQoL) and transfer activities in patients with Parkinson's disease (PD). Background: Bradykinesia, rigidity, tremor and…123I-FP-CIT SPECT imaging in early PD patients versus mid and late onset PD: Longitudinal data from the PPMI study
Objective: To determine whether there are longitudinal differences in dopaminergic denervation [as exemplified by signal reduction in 123I-FP-CIT SPECT] in early PD patients versus mid…Validation of the PREDIGT Score for the Incidence Rate of Parkinson disease
Objective: To assess the discriminative power of the PREDIGT formula for incident Parkinson disease (PD). Background: The inability to predict the incidence rate of PD…High intensity interval training elevates circulating BDNF and miRNAs level in patients with idiopathic Parkinson’s disease
Objective: To investigate if twelve weeks of high intensity interval training (HIIT) can enhance serum BDNF and miRNAs levels in patients with Parkinson’s disease (PD). Background: BDNF plays several important physiological functions including…Parkinson’s disease-associated mutations of PLA2G6 alters the membrane dynamics and α-synuclein stability
Objective: To investigate the mechanism of α-synuclein (α-Syn) aggregation. Background: PLA2G6 has been isolated as the gene responsible for an autosomal recessive form of Parkinson’s…Glabellar tap predicts dopamine transporter deficiency in parkinsonism
Objective: The objective of this study was to investigate the association between glabellar tap findings with nigrostriatal dopamine function in patients with unclear parkinsonism. Background:…Comorbid Parkinson’s disease in a Korean patient with Alexander’s disease
Objective: We report a unique case of genetically diagnosed Alexander's disease comorbid, with clinically diagnosed Parkinson's disease. Background: Alexander disease is a neurological disease, that causes…