Unraveling biological processes implicated in MSA and PD by transcriptomic analysis
Objective: To find differential biological processes between synucleinopathies (MSA and PD). Background: Multiple system atrophy (MSA) is an oligodendroglial sinucleinopathy that is often misdiagnosed as…Braak model in Parkinson disease using MRI biomarkers
Objective: The aim of this study was to test using multimodal MRI biomarkers if the pattern of neurodegeneration in the brain of patients with PD…A Lewy body disease of widely confirmed Lewy bodies in the cerebral cortexes including the occipital lobe without pathological changes in the hippocampal CA2/3 region
Objective: We present Lewy body disease (LBD) showing unique neuropathological findings which are widely recognized Lewy bodies (LBs) in the cerebral cortexes including the occipital…BST1 rs4698412 allelic variant increases the risk of gait or balance deficits in patients with Parkinson’s disease
Objective: We aimed to explore effects of bone marrow stromal cell antigen‐1 (BST1) rs4698412 allelic variant on brain activation and associative clinical symptoms in Parkinson’s…Exercise and physical activity for people with Progressive Supranuclear Palsy
Objective: To (i) evaluate the literature on exercise and physical activity for Progressive Supranuclear Palsy and (ii) make PSP-specific recommendations for exercise programs and trial…The congruence of asymmetry between motor symptoms and retinal thickness in Parkinson’s disease
Objective: To analyze the relationship between interocular difference of retinal thickness and motor asymmetry in Parkinson’s disease (PD). Background: It is known that the early…Deep mitochondrial sequencing in Parkinson’s disease reveals possible genetic modifiers of reduced penetrance in Parkin/PINK1 mutation carriers
Objective: To discover potential penetrance biomarkers in mitochondrial DNA (mtDNA) for Parkin and PINK1 mutation carriers. Background: Biallelic mutations in Parkin and PINK1 are fully…Freezing of gait as a reflection of disturbed general time processing in Parkinson’s disease? A new look on a complex phenomenon
Objective: The aim of the study is to assess the association of freezing of gait (FoG) with disturbed time processing in Parkinson´s disease (PD) by…The relationship between constipation and alteration of gut microbiota in patients with Parkinson’s disease
Objective: To study compositional and functional differences in the gut microbiota and its products between individuals with PD and matched controls,and these differences are or…Sustained release triple drug loaded Microbaloons for management of Parkinson’s Disease
Objective: It is hypothesized that a drug delivery system that provides controlled and sustained release of PD drugs would afford better management of PD. Hollow…
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