Virtual Reality EEG guided motor neurofeedback training has mid-term effects in Parkinson’s Disease Patients limits of stability
Objective: To prove the effects of a virtual reality (VR) EEG guided motor Neurofeedback (NFB) training protocol on stability and gait of non-demented HY I-III…Simple Partial Status Epilepticus Presenting With Dystonic Features In Acute Stroke
Objective: We describe a case of a patient with an acute stroke who presented with abnormal posturing and tremulous movements of the right upper extremity,…Advanced autonomous motor state detection from wrist-worn sensor in persons with PD
Objective: To explore the advancement of precision and granularity of motor state detection in persons with PD (PwP) from wrist-worn sensor data. Background: The motor…Activity of Cerebral Networks, Amyloid and Microglia in Corticobasal Syndrome: the ActiGliA study
Objective: The purpose of this prospective cohort study is to analyse the topographical and temporal relationship between cerebral microglia activity changes, network degeneration and atrophy…Stability and reliability of objective measures of speech in Parkinson’s Disease over 12 months
Objective: To describe the stability and reliability of acoustic measures of speech in Parkinson’s Disease (PD) at 3 and 12 months. Background: Speech biomarkers hold…Correlation between structural neuroimaging and clinical outcomes in a small sample of patients with early Huntington’s disease
Objective: Scores on the symbol digit modalities test (SDMT), Stroop word-reading, Total Motor Score (TMS) and composite UHDRS (cUHDRS) are correlated with disease progression and…Seeking regulatory feedback on novel clinical outcome assessments: a case example from the Huntington’s Disease – Regulatory Science Consortium (HD-RSC)
Objective: To align with regulators on the utility and development strategy of novel clinical outcome assessments for use in Huntington’s disease (HD) clinical trials. Background:…A safety, tolerability and biomarker update from an ongoing open-label extension study of RG6042 in adults with early manifest Huntington’s disease
Objective: To present the safety, tolerability and biomarker effects of RG6042 (previously, IONIS-HTTRX) during an open-label extension (OLE) study in adults with early manifest Huntington’s…Onset of action for rimabotulinumtoxinB in the treatment of adult sialorrhea
Objective: To assess the onset of action for rimabotulinumtoxinBinjections in the salivary glands for the treatment of sialorrhea. Background: Sialorrhea (drooling) causes significant morbidity including impaired oral…Incidence of treatment-emergent adverse events in Parkinson’s disease patients according to baseline MAO-B inhibitors use: post-hoc analysis from double-blind combined BIPARK-I and II data
Objective: To evaluate the incidence of treatment-emergent adverse events (TEAEs) in levodopa-treated Parkinson’s Disease (PD) patients with motor fluctuations and taking opicapone (OPC). Background: OPC…
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