Longitudinal analysis of the modified Hoehn and Yahr disease stage in PD-1101, a Phase 1b clinical study of VY-AADC01
Objective: To describe changes over the first year in disease severity and activities of daily living using modified Hoehn and Yahr (mH&Y) stage and UPDRS…Social Network for the diagnosis of RLS
Objective: Identify patients with RLS using social media, describe time of evolution, previous diagnosis, treatment, symptoms severity and quality of life perception. Background: RLS is a…Pilot Study Comparing Home Sleep Profiler to In-laboratory Polysomnogram for REM Sleep Behavior Disorder Diagnosis
Objective: To compare the Sleep Profiler (SP), an FDA-approved device for home evaluation of sleep disorders, to the gold standard sleep laboratory polysomnogram (PSG) in…“So much easier”; patient’s perceptions of Virtual Clinics for Parkinson’s Disease
Objective: Our virtual clinic for People with Parkinson’s disease (PwP) is a service innovation, providing a consultation with a Parkinson’s clinic doctor via telephone, with…Motor and non-motor symptoms burden, autonomy, quality of life and principal caregiver status is worse in patients with 5-2-1 positive criteria: a simple screening tool for identifying PD patients who need an optimization of Parkinson´s treatment.
Objective: To compare quality of life (QoL), non-motor symptoms (NMS) burden, autonomy for activities of daily living (ADL) and patient´s principal caregiver status in PD…Relationship between Progressive Supranuclear Palsy and Caregiver Burden
Objective: To understand the relationship between progressive supranuclear palsy (PSP) disease progression and caregiver requirement and burden. Background: PSP is a rare neurodegenerative disease, and…Pulmonary function in patients with Parkinson’s disease
Objective: Analyse the pulmonary function in patients with PD. Background: Respiratory disorders are the most common causes of death in people with Parkinson's disease (PD)(1,2).…Clinical and fMRI effects of Action Observation and Motor Imagery Training on dual-task performances in Parkinson’s disease patients with postural instability and gait disorders
Objective: To assess brain functional reorganization and gait changes performing dual-task after 6 weeks of action observation training (AOT) and motor imagery (MI) associated with…Botulinum toxin treatment of muscle spasms in a case of Satoyoshi syndrome
Objective: To describe improvement in muscle spasms of the jaw and upper limb associated with Satoyoshi syndrome using botulinum toxin injections. Background: Satoyoshi syndrome is…Plasma membrane Ca2+ Atpase 1 as a candidate to mediate the degeneration of dopaminergic neurons by inflammation in Parkinson’s disease
Objective: To identify genes involved in the degeneration of the dopaminergic neurons (DN) of the substantia nigra (SN) by inflammation. Background: Parkinson’s disease (PD) is…
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