Effects of exosomes devised from dopaminergic neurons overexpressing α-synuclein on autophagy and inflammation in microglia
Objective: The aim of this study was to investigate whether the exosomes secreted by dopaminergic neurons over-expressing α-synuclein could regulate the inflammation of microglia via…The Influence of 3-Phenoxybenzoic Acid in Dopaminergic Degeneration
Objective: 3-phenoxybenzoic acid (3-PBA) is a metabolite of Fenpropathrin (FEN). The emphasis of this paper is on the relationship between 3-PBA and Dopaminergic Degeneration. Background:…Quantitative susceptibility mapping images for the parcellation of the Subthalamic Nucleus: a possible role for targeting Deep Brain Stimulation
Objective: To investigate the iron distribution in STN in PD patients using QSM images. Background: Subthalamic Deep Brain Stimulation (DBS) is considered an effective treatment…Right hemispheric β-amyloid deposition associates with freezing of gait in Parkinson’s disease
Objective: To investigate regional cerebral deposition of β-amyloid in patients with Parkinson's disease (PD) who have freezing of gait (FoG). Background: FoG is one of…Retinal thinning and disease worsening in Lewy body diseases
Objective: To assess longitudinal changes of retinal thickness measurements and their role as biomarkers of disease progression in patients with Lewy body diseases (LBDs). Background:…Iron Imaging as a Diagnostic Tool for Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: We performed a systematic meta-analysis of SN iron imaging studies in PD to better understand the role of iron-sensitive MRI quantification to distinguish patients…Alpha-synuclein preformed fibril (PFF)-triggered synucleinopathy recapitulates neurochemical features of human PD: A PET study in rats
Objective: To investigate longitudinal dopaminergic deficits and similarity to human Parkinson’s disease (PD) using PET imaging in the rat alpha-synuclein (a-syn) preformed fibril (PFF) model.…In vivo markers of anxiety in drug-naïve Parkinson’s disease
Objective: To investigate imaging and CSF markers of disease pathology associated with anxiety in drug-naïve idiopathic Parkinson’s disease (PD) patients. Background: Anxiety is a frequent…Walking and Turning of Parkinson’s Disease – Impacts of Freezing of Gait
Objective: This study aimed to find the comprehensive characteristics of locomotion in PD, including forward- and backward walking and turning, especially the impact of FoG.…LFP in motor subtypes of Parkinson’s disease
Objective: To evaluate the power spectrum of LFPs in motor subtypes of Indian PD patients. Background: Though the motor subtypes of the Parkinson’s disease (PD)…
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