Ceftriaxone improves motor function in a rat hemi-parkinsonian model: Potential to delay bilateral progression of motor deficits in Parkinson’s disease
Objective: This study sought to evaluate the impact of ceftriaxone, as a potential repurposed drug, in ameliorating motor decline in a unilateral rat 6-hydroxydopamine (6-OHDA)…Comparison of the effect of hydroalcoholic extract of olive leaf and levodopa on reducing parkinson’s symptoms in animal model
Objective: Today, the use of medicinal herbs to prevent and slow down the progression of Parkinson's disease has attracted the attention of researchers. The phenolic…Anticholinergic Burden in Parkinson’s Disease Patients in India – A Hospital Based Study
Objective: To determine the cumulative anticholinergic burden in Indian Parkinson’s disease (PD) patients and to correlate the same with cognitive impairment and gait disturbance. Background:…Effects of a next-generation neurotrophic compound in a toxin model of Parkinson’s disease
Objective: Investigate the effects of a peripherally administered novel neurotrophic compound, CMx01a, in 6-hydroxydopamine rat model of Parkinson’s disease. Background: Neurotrophic factors are promising drug…Brain 5-HT1 receptor binding in multiple system atrophy: A [18F]-MPPF PET study
Objective: The primary objective was to compare brain 5-HT1a receptor binding between patients with multiple system atrophy (MSA) and healthy controls (HC). The secondary objectives…Glucocerebrosidase activity and atypical parkinsonism: a multi-centre exploratory study
Objective: We aimed to determine the frequency of Glucocerebrosidase (GBA) deficiency (subclinical Gaucher's Disease type 1, GD1) in patients with atypical parkinsonism (AP) with features…Key neuropathological features separating corticobasal degeneration from other related disorders
Objective: This study investigated the key neuropathological features that could separate corticobasal degeneration (CBD) from related parkinsonian disorders by using a decision tree algorithm. Background:…Staircase sign for Atypical and Secondary parkinsonism
Objective: The aim of this study was to investigate the difference in the preference of staircase climbing in PD and atypical/ secondary parkinsonism when they…Benign Infantile Tremor Syndrome (BITS): a new movement disorder
Objective: We present infants at our institution presented with action tremor with onset weeks to months later after birth and otherwise similar to neonatal jitteriness. Background: Several benign movement disorders in infancy have been described including…Simultaneous, levodopa-responsive Holmes’ tremor and hemiparkinsonism due to midbrain cavernous malformation
Objective: We report a case of concomitant Holmes’ tremor (HT) and hemiparkinsonism (HP) attributable to a single structural lesion with robust clinical response to levodopa.…
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