Pulmonary function in Parkinson’s disease
Objective: To establish if pulmonary function is impaired in Parkinson’s disease (PD) and define any pattern of impairment. Background: Parkinson’s disease (PD) is associated with…Impulse Control Disorders and Other Psychiatric Complications in a Series of Patients Treated Levodopa-Carbidopa Instestinal Gel
Objective: To determine the frequency of ICDs and other psychiatric complications in a serie of patients of the Movement Disorders Unit of our center, treated…Psychiatric comorbidities in Young Onset Parkinson’s disease
Objective: The study aims at exploring psychiatric comorbities;namely;anxiety,depression and impulse control disorders(ICD) and their inter relationship in a large cohort of Young onset PD(YOPD)patients. Background:…Population pharmacokinetic analysis of levodopa and carbidopa after subcutaneous administration with and without adjunct oral therapy
Objective: To develop population pharmacokinetic (PK) models for levodopa (LD) and carbidopa (CD) following subcutaneous (SC) infusion, including adjunct oral LD/CD administration. Background: ND0612 is…A Long-Term Safety, Tolerability, and Efficacy Study of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Interim Results
Objective: Evaluate the long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL-130277; APL) for on-demand treatment of “OFF” episodes in patients with Parkinson’s…The exosomal a-syn filaments can be a novel biomarker of Parkinson’s disease
Objective: This study is aimed to investigate whether the number of exosomes, the amount of total or exosomal a-synuclein (a-syn) filaments in serum can serve as…Pharmacokinetics and Biomarker Changes in NILO-PD, A Phase 2A Study of Nilotinib in Patients with Moderate to Advanced Parkinson’s Disease
Objective: To assess serum pharmacokinetics (PK) and cerebrospinal fluid (CSF) concentrations of nilotinib as well as CSF biomarker changes in NILO-PD study. Background: Several cell…Types of Pain in Parkinson`s Disease Patients
Objective: To present the characteristics of four different types of pain in Parkinson`s disease (PD) patients. Background: Neurodegeneration can cause a nociceptive disturbances at many…Deep Brain Stimulation impact on Social and Occupational Function in Parkinson’s Disease with Early Motor Complications
Objective: To investigate the effect of DBS compared with BMT on social, psychosocial and occupational functioning in PD patients ≤ 60 years of age with…Effect of Lactobacillus casei supplementation on clinical response, gut microbiota and faecal metabolites in patients with Parkinson’s disease: A randomized, double-blind, placebo-controlled trial
Objective: To evaluate the effect of Lactobacillus casei strain Shirota (LcS) supplementation on symptoms, gut microbiota and faecal metabolites in patients with Parkinson's disease (PD).…
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