Perillyl alcohol restores mitochondrial dysfunction and abridge NLRP3 inflammasomes activation in in-vitro and in-vivo model of Parkinson’s disease
Objective: Parkinson's disease (PD) affects around 2-3% population of age greater than 65 and is the second most common neurogenerative disorder. The molecular mechanism underpinning…Validation of MDS-UPDRS-based score to predict conversion to freezing of gait in Parkinson’s disease
Objective: To validate an MDS-UPDRS component score for predicting conversion to freezing of gait in Parkinson’s disease. Background: Freezing of gait (FOG) is a debilitating…Treatment of hemichorea-hemiballism with valbenazine
Objective: To describe a video-case report of hemichorea-hemiballism improved by valbenazine therapy Background: Hemichorea-hemiballism (HCHB) is an uncommon movement disorder with numerous etiologies including structural…Real-World Healthcare Resource Utilization in Patients with Parkinson’s Disease and Motor Fluctuations
Objective: To evaluate healthcare resource utilization (HCRU) patterns in patients with Parkinson’s disease (PD) and motor fluctuations (MF) with carbidopa/levodopa (CD/LD) and other adjunctive PD…Trends and Racial Disparities of Palliative Care Use among Hospitalized Patients with Parkinson’s Disease
Objective: To analyze the rate of palliative care consultations among hospitalized patients with Parkinson’s Disease (PD) using the National Inpatient Sample data from 2007 to…Discrimination of alpha-synuclein strains and sub-strains in Synucleinopathies
Objective: To differentiate and characterize alpha-synuclein strains and sub-strains associated with synucleinopathies. Background: Synucleinopathies are a diverse group of neurodegenerative diseases characterized by misfolding aggregation…Parkinson’s disease patients at Hoehn and Yahr stage 1 show deficits in reactive but not proactive inhibitory control
Objective: We wanted to assess whether i) Parkinson’s disease (PD) patients at Hoehn and Yahr (HY) stage 1 show a global or a selective impairment…Baseline Predictors of Constipation and Probable Rapid Eye Movement Sleep Behavior Disorder (pRBD) for Cognitive Impairment After 5 Years of Parkinson’s Disease (PD) Diagnosis in the Parkinson’s Progression Markers Initiative Cohort (PPMI)
Objective: Cognitive impairment is linked to morbidity and mortality in patients with PD, this study aims to investigate whether the presence of constipation and RBD…What can tell us Non-Motor Symptoms about Cognition and Gait in the Early Stage of PD Patients
Objective: To describe the motor, cognitive and non-motor profiles in the early stage of PD using eMotion Kinect system, Moca Test and PD-CRS. Background: The…Does age at onset of Parkinson’s disease affect the development of dementia?
Objective: To investigate whether progression to dementia in senile Parkinson’s disease, SPD, (disease onset after 70 years) differs from that in old Parkinson’s disease, OPD,…
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