MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2020

    Olfactory dysfunction and its relationship with clinical features of Parkinson’s disease

    Y.J Zhou, R.C He, Y.W Zhao, XX. Yan, B.S Tang, J.F Guo (Changsha, China)

    Objective: To investigate the reliability of assessing olfactory function of patients with PD by HRS in China and compare other non-motor features between patients with PD…
  • MDS Virtual Congress 2020

    Sensorimotor inhibition relates to gait dysfunction in people with Parkinson’s disease

    D. Martini, G. Harker, R. Morris, J. Nutt, F. Horak (Portland, OR, USA)

    Objective: To determine how sensorimotor inhibition relates to objective measures of gait OFF and ON levodopa and how having Parkinson’s disease (PD) affects this relationship.…
  • MDS Virtual Congress 2020

    Increased epinephrine in the saliva of Parkinson’s disease patients: A preliminary observation

    P. Wichit, S. Thanprasertsuk, T. Hopetrungraung, O. Phokaewvarangkul, S. Bongsebandhu-phubhakdi, R. Bhidayasiri (Bangkok, Thailand)

    Objective: To investigate the levels of dopamine (DA), norepinephrine (NE), epinephrine (EPI) and serotonin (5-HT) in the saliva of Parkinson’s disease (PD) patients and compare…
  • MDS Virtual Congress 2020

    Association between impulse control disorders and depression in drug-naïve Parkinson’s disease

    A. Karukote, S. Thakolwiboon, P. Julayanont (Lubbock, TX, USA)

    Objective: To determine the association between depression and impulse control disorders (ICDs) in patients with Parkinson's disease (PD). Background: Depression is one of the most…
  • MDS Virtual Congress 2020

    WATCH-PD: Wearable Assessments in the Clinic and Home in Parkinson’s Disease: Study Design and Update

    J.L Adams, E.R Dorsey, A. Steinman, T. Kangarloo, R. Alexander, B. Tracey, N. Zach, R. Rubens, M. Kostrzebski, M. Bockus, R. O'Loughlin, E.A Stevenson, J. Cosman (Rochester, NY, USA)

    Objective: To determine whether digital measures can provide a progression profile in early Parkinson’s disease (PD) that is more sensitive and/or less variable than current…
  • MDS Virtual Congress 2020

    MOve To ImprovE physical activity in Parkinson’s disease (MOTIvatE): A pilot randomized clinical trial of gamification

    N. Dahodwala, M. Engeland, W. Kerr, L. Walsh, M. Patel (Philadelphia, PA, USA)

    Objective: To test the feasibility and impact of a behaviorally designed gamification intervention to improve goal-directed behavior assessed by physical activity levels in Parkinson’s disease…
  • MDS Virtual Congress 2020

    Safety and Tolerability of Burst Cycling Deep Brain Stimulation for Freezing of Gait in Parkinson’s Disease

    W. Hu, J. Wang, R. Barmore, J. Melo Lobo, T. Tsuboi, A. Wang, A. Ramirez-Zamora, M. Okun, L. Almeida (Gainesville, FL, USA)

    Objective: To determine the safety and tolerability of burst cycling deep brain stimulation (DBS) in Parkinson's disease (PD) patients experiencing freezing of gait (FoG). Background:…
  • MDS Virtual Congress 2020

    Application of PKG System for Objective Measurement and Early Identification in Parkinson’s Disease

    C. Lina, C. Guoen, W. Huidan, W. Yingqing, C. Ying, C. Xiaochun, Y. Qinyong (Fuzhou, China)

    Objective: This study aimed to assess the correlations of the PKG data with clinical scores of bradykinesia, rigidity and tremor. Background: The treatment of levodopa…
  • MDS Virtual Congress 2020

    A Long-Term Safety, Tolerability, and Efficacy Study of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in De Novo vs Rollover Patients With Parkinson’s Disease: Interim Results

    R. Pahwa, S. Fox, C. Singer, P. Bhargava, B. Navia (Kansas City, KS, USA)

    Objective: Evaluate long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL-130277; APL) for on-demand treatment of “OFF” episodes in de novo (DN) vs…
  • MDS Virtual Congress 2020

    Phase I Study Design of a Leucine-Rich Repeat Kinase 2 (LRRK2) Antisense Oligonucleotide, for Parkinson’s Disease

    J. Shirvan (Cambridge, MA, USA)

    Objective: We will present the preclinical efficacy and safety data and the design of the first in human trial of an antisense oligonucleotide (ASO) for…
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